Results 81 to 90 of about 6,563 (212)

Guideline for the diagnosis, treatment, and prevention of respiratory syncytial virus infection in children in China

Pediatric Investigation, Volume 9, Issue 3, Page 205-220, September 2025.
ABSTRACT Respiratory syncytial virus (RSV) is one of the most common respiratory pathogens in children under 5 years of age worldwide and it seriously threatens children's health. In recent years, great progress has been made in the field of RSV‐related diseases.
Committee of Pediatrics, China Medical Education Association, Subspecialty Group of Respiratory Diseases, Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of China Non‐public Medical Institution Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China Medical News and Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, Global Pediatric Respiratory Alliance, Beijing Hairun Charity Foundation   +16 more
wiley   +1 more source

A viral metagenomic survey identifies known and novel mammalian viruses in bats from Saudi Arabia.

PLoS ONE, 2019
Bats are implicated as natural reservoirs for a wide range of zoonotic viruses including SARS and MERS coronaviruses, Ebola, Marburg, Nipah, Hendra, Rabies and other lyssaviruses.
Nischay Mishra, Shamsudeen F Fagbo, Abdulaziz N Alagaili, Adam Nitido, Simon H Williams, James Ng, Bohyun Lee, Abdulkareem Durosinlorun, Joel A Garcia, Komal Jain, Vishal Kapoor, Jonathan H Epstein, Thomas Briese, Ziad A Memish, Kevin J Olival, W Ian Lipkin   +15 more
doaj   +1 more source

Malpais spring virus is a new species in the genus vesiculovirus [PDF]

, 2013
BACKGROUND: Malpais Spring virus (MSPV) is a mosquito-borne rhabdovirus that infects a variety of wild and feral ungulates in New Mexico, including horses and deer. Although, initial serologic tests and electron microscopy at the time of isolation nearly
Amelia PA Travassos da Rosa, Edward C Holmes, Nikos Vasilakis, Peter J Walker, Robert B Tesh, Steven Widen, Thomas G Wood   +6 more
core   +1 more source

Exploring Therapeutic Targets From Spreading Patterns Against Respiratory Syncytial Virus

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
RSV spreads through three main modes of infection: receptor‐dependent infection of free viral particles, syncytia formation, and transmission via actin filaments. CX3CR1, CCR3, and HSPG mediate viral adsorption; the IGF1R signaling pathway facilitates viral internalization by recruiting NCL to the membrane surface, and the RHO GTPase and PI3K signaling
Han Zhang, Zhao Zhang, Yixuan Yang, Jingjing Pei   +3 more
wiley   +1 more source

Complete Protection against Influenza Virus H1N1 Strain A/PR/8/34 Challenge in Mice Immunized with Non-Adjuvanted Novirhabdovirus Vaccines. [PDF]

PLoS ONE, 2016
Novirhabdoviruses like Viral Hemorrhagic Septicemia Virus (VHSV) and Infectious Hematopoietic Necrosis Virus (IHNV) are fish-infecting Rhabdoviruses belonging to the Mononegavirales order. By reverse genetics, we previously showed that a recombinant VHSV
Ronan N Rouxel, Emilie Mérour, Stéphane Biacchesi, Michel Brémont   +3 more
doaj   +1 more source

Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 [PDF]

, 2014
In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa.
Andersen, Kristian G., Baize, Sylvain, Bavari, Sina, Berthet, Nicolas, Blinkova, Olga, Brister, J. Rodney, Bào, Yīmíng, Clawson, Anna N., Fair, Joseph, Formenty, Pierre, Gabriel, Martin, Garry, Robert F., Gire, Stephen K., Goba, Augustine, Gonzalez, Jean-Paul, Günther, Stephan, Happi, Christian T., Jahrling, Peter B., Kapetshi, Jimmy, Kobinger, Gary, Kugelman, Jeffrey R., Kuhn, Jens H., Leroy, Eric M., Maganga, Gael Darren, Mbala, Placide K., Moses, Lina M., Muyembe-Tamfum, Jean-Jacques, Nichol, Stuart T., N’Faly, Magassouba, Omilabu, Sunday A., Palacios, Gustavo, Park, Daniel J., Paweska, Janusz T., Radoshitzky, Sheli R., Rossi, Cynthia A., Sabeti, Pardis C., Schieffelin, John S., Schoepp, Randal J., Sealfon, Rachel, Swanepoel, Robert, Towner, Jonathan S., Wada, Jiro, Wauquier, Nadia, Yozwiak, Nathan L.   +43 more
core   +5 more sources

Engineering multiple levels of specificity in an RNA viral vector [PDF]

, 2020
Synthetic molecular circuits could provide powerful therapeutic capabilities, but delivering them to specific cell types and controlling them remains challenging.
Chong, Lucy S., Elowitz, Michael B., Gao, Xiaojing J., Ince, Michaela H., Kim, Matthew S.   +4 more
core   +1 more source

Marburg Virus Disease: A Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati, Somayeh Sadat Hosseini Fakhr, Ali Qaraee Najafabadi, Negin Karami, Hassan Karami   +4 more
wiley   +1 more source

A conserved motif in Henipavirus P/V/W proteins drives the fibrillation of the W protein from Hendra virus

Protein Science, Volume 34, Issue 4, April 2025.
Abstract The Hendra (HeV) and Nipah (NiV) viruses are high‐priority, biosafety level‐4 pathogens that cause fatal neurological and respiratory disease. Their P gene encodes not only the P protein, an essential polymerase cofactor, but also the virulence factors V and W.
Frank Gondelaud, Christophe Bignon, Denis Ptchelkine, Frédéric Carrière, Sonia Longhi   +4 more
wiley   +1 more source

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5 [PDF]

, 2011
The 5'-cap-structures of higher eukaryote mRNAs are ribose 2'-O-methylated. Likewise, a number of viruses replicating in the cytoplasm of eukayotes have evolved 2'-O-methyltransferases to modify autonomously their mRNAs.
A Ghosh, A Nomoto, A Pichlmair, AM Waterhouse, B Morin, Benjamin W Neuman, BS Schnierle, Burkhard Ludewig, CA Janeway Jr., DJ Hui, E Decroly, EJ Snijder, F Terenzi, G Bocharov, G Uzé, H Hemmi, H Kato, H Zhou, J Reguera, JK Roth-Cross, John Ziebuhr, K Bryson, K Karikó, KK Eriksson, KM Rose, Kristy J Szretter, L Cervantes-Barragan, L Cervantes-Barragán, L Gitlin, Luisa Cervantes-Barragan, M Bouvet, M Feder, M Schlee, Matthias Habjan, Michael S Diamond, O Haller, O Le Gall, O Takeuchi, R Gosert, R Züst, Reinhard Maier, Roland Züst, S Daffis, S Shuman, S Wünschmann, SR Nallagatla, SR Nallagatla, Stuart G Siddell, Susan C Baker, V Hornung, V Thiel, Volker Thiel, Winfried Barchet, Y Chen, YM Loo, YM Loo   +55 more
core   +1 more source