Results 161 to 170 of about 8,015 (197)

Immediate intraoperative detrusor muscle status at primary transurethral resection of bladder tumour: a prospective, blinded, paired cohort, feasibility study using fluorescence confocal microscopy (IB1‐LaserComplete study)

BJU International, Volume 138, Issue 4, Page 705-713, October 2026.
Objectives To evaluate ex vivo fluorescence confocal microscopy (FCM) for immediate detrusor muscle (DM) assessment during primary transurethral resection of bladder tumour (TURBT). Patients and Methods This prospective, blinded, paired‐cohort feasibility study enrolled consecutive patients undergoing primary TURBT for suspected non‐muscle‐invasive ...
Martin J. Connor, Archana Gopalakrishnan, Nikhil Mayor, Eva Bolton, Sami Hamid, Sai Kalpitha Reddy, Tayla Perreau, Eslam Maher, Alexander Light, Samuel Morris, Jiten Jaipura, Mariana Bertoncelli Tanaka, Norma Gibbons, Archie Hughes‐Hallett, Hashim U. Ahmed, Rakesh Heer, Andrew Smith, David Hrouda, Anna Silvanto, Mona El‐Bahrawy, Mathias Winkler   +20 more
wiley   +1 more source

Pericentrosomal Redistribution of the Endoplasmic Reticulum Ensures Organelle Symmetric Inheritance and Mitotic Progression

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu, Yalin Liu, Rongyi Wang, Wenwen Xu, Hao Shi, Ning Huang, Junlin Teng, Jin Meng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery

Advanced Science, Volume 13, Issue 53, 24 September 2026.
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le, P. Thien Phan, Lachlan Fitzgerald, P. Ross McAree, T. Nho Do, T. Thang Vo‐Doan   +5 more
wiley   +1 more source

Speech Biomarkers for Quantifying Effects of Subthalamic Deep Brain Stimulation in Parkinson's Disease

Annals of Neurology, Volume 100, Issue 3, Page 628-640, September 2026.
Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže, Mário Sousa, Vojtěch Illner, Adriana Jorge, Matilde Castelli, Ines Debove, Andreia D. Magalhães, Julia Waskönig, Lenard Lachenmayer, Joan Philipp Michelis, Gerd Tinkhauser, Deborah Amstutz, Marie Elise Maradan‐Gachet, Katrin Petermann, Claudio Pollo, Tobias Nef, Paul Krack, Jan Rusz   +17 more
wiley   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

Epilepsia, Volume 67, Issue 9, Page 4758-4773, September 2026.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni, Karine Brochu, Paolo Federico, Walter Hader, Julia W. Y. Kam, Fady Girgis   +5 more
wiley   +1 more source

Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy

Epilepsia, Volume 67, Issue 9, Page 4828-4842, September 2026.
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger, Xinbing Zhang, Thomas Lisko, Hafsa Farooqi, Steffen Ventz, Sandipan Pati, Thomas R. Henry, David P. Darrow, Michael C. Park, Theoden I. Netoff, Robert A. McGovern   +10 more
wiley   +1 more source

Deletion of Astrocytic TNFR1 Attenuates Hyperexcitability and Initiation of Epileptogenesis

Glia, Volume 74, Issue 9, September 2026.
Inducible, astrocyte‐specific deletion of TNFR1 reduces basal EEG spectral power. Loss of astrocytic TNFR1 attenuates acute seizure activity in two distinct experimental models of epilepsy. Deletion of TNFR1 in astrocytes limits epilepsy development and hippocampal pathology in a mouse model of temporal lobe epilepsy with hippocampal sclerosis ...
Lukas Henning, Ioannis Zalachoras, Giovanni Carriero, Gerald Seifert, Peter Bedner, Christian Steinhäuser, Andrea Volterra   +6 more
wiley   +1 more source

High‐Resolution Diffusion Tensor Imaging of the Hippocampus and Associations With Neuropsychiatric Symptoms in Lewy Body Diseases

Hippocampus, Volume 36, Issue 5, September 2026.
ABSTRACT Parkinson's disease (PD) encompasses motor and neuropsychiatric symptoms (NPS) including depression, anxiety, and apathy. Cognitive subtypes—PD with mild cognitive impairment (PD‐MCI) and PD with dementia (PDD)—and the related Dementia with Lewy Bodies (DLB) exist within the spectrum of Lewy body disease (LBD).
Alexandra S. Budd, Kevin Grant Solar, Myrlene Gee, Krista Nelles, Brooklyn Mankasingh, Zahinoor Ismail, Eric E. Smith, Michael Martyna, Fang Ba, Sanjay Kalra, Christian Beaulieu, Richard Camicioli   +11 more
wiley   +1 more source

Transoral Robotic Resection of Pediatric Tongue Base Mucoepidermoid Carcinoma

The Laryngoscope, Volume 136, Issue 9, Page 4043-4048, September 2026.
Transoral robotic surgery (TORS) offers a precise, minimally invasive approach for the management of rare pediatric tongue base malignancies. Intraoperative visualization demonstrates accurate tumor delineation and controlled resection, while postoperative findings confirm effective oncologic clearance with preservation of surrounding structures.
Krisztina Somogyvári, Kinga Jakab‐Péter, Tamás Tornóczki, Krisztián Molnár, István Szanyi   +4 more
wiley   +1 more source

Evaluation of Third‐Order Motion‐Compensated Cardiac Diffusion Tensor Imaging Across Cardiac Phases Using an Ultra‐High‐Performance Clinical Scanner

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1365-1378, September 2026.
ABSTRACT Purpose To evaluate a third‐order motion‐compensated spin echo (M3‐MCSE) sequence at multiple cardiac phases on a clinical 3 T MRI scanner with ultra‐high performance (UHP) gradients (200 mT/m), compared with stimulated echo acquisition mode (STEAM) and second‐order MCSE (M2‐MCSE) for cardiac diffusion tensor imaging (cDTI).
Ke Wen, Pedro F. Ferreira, Alberto Di Biase Oemick, Ricardo Wage, Karl P. Kunze, Fanwen Wang, Dudley J. Pennell, Andrew D. Scott, Sonia Nielles‐Vallespin   +8 more
wiley   +1 more source