Results 231 to 240 of about 129,978 (318)

Generative Multiobjective Bayesian Optimization with Scalable Batch Evaluations for Sample-Efficient De Novo Molecular Design. [PDF]

Ind Eng Chem Res
Muthyala MR, Sorourifar F, Tan T, Peng Y, Paulson JA.   +4 more
europepmc   +1 more source

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

ATR-FTIR Spectroscopy of Saliva and Machine Learning as a Screening Test for Sjögren Disease. [PDF]

Anal Chem
Contreras J, Vyas B, Ryabchykov O, Larsen M, Gildener-Leapman N, Bocklitz T, Popp J, Lednev IK.   +7 more
europepmc   +1 more source

Generalized Chemical Model for Warm Dense Hydrogen: Ionization Potential Depression and Molecular Dissociation Shifts

Contributions to Plasma Physics, EarlyView.
ABSTRACT Warm dense matter (WDM) is a complex state, where quantum effects, thermal excitations, and strong interparticle correlations coexist. Understanding its microscopic composition and medium‐induced modifications of atomic and molecular properties is essential for planetary modeling, fusion research, and high‐energy‐density experiments.
L. T. Yerimbetova, Yu. V. Arkhipov, Ye. S. Mukhametkarimov, A. E. Davletov, I. M. Tkachenko   +4 more
wiley   +1 more source

Photochemical Chain Scissions Enhance Polyethylene Glycol Biodegradability: from Probabilistic Modeling to Experimental Demonstration. [PDF]

Environ Sci Technol
Kleemann K, Jaggi M, Bernasconi SM, Schmitz RA, Künkel A, Simon C, McNeill K, Battagliarin G, Sander M.   +8 more
europepmc   +1 more source

Enhanced Ultramicropore of Biomass‐Derived Porous Carbon for Efficient and Low‐Energy CO2 Capture: Integration of Adsorption and Solar Desorption

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
By increasing the ultramicropore volume of biomass‐derived porous carbon through mechanical compression and utilizing its photothermal properties, this study achieves high CO2 adsorption capacity and solar‐driven regeneration with low energy consumption, providing a novel strategy for high‐efficiency carbon capture technology.
Pengcheng Guo, Ruiqi Xue, Qiao Zou, Xiancheng Ma, Changqing Su, Zheng Zeng, Liqing Li   +6 more
wiley   +1 more source

Machine learning driven acceleration of biopharmaceutical formulation development using Excipient Prediction Software (ExPreSo). [PDF]

Comput Struct Biotechnol J
Vidal-Henriquez E, Holder T, Lee NF, Pompe C, Teese MG.   +4 more
europepmc   +1 more source

Subatomic Particle Simulations using Monte Carlo and Molecular Dynamics Algorithms to Simulate Stable Atom and Model Electronic Structures

S. Venkatesan
openalex   +2 more sources

Spider Silk Inspired Shape Adaptive and Heat Conductive Thermal Interface Materials

Electron, EarlyView.
Inspiring by the architecture of spider silk, a semicrystalline PVDF polymer emerges selective crystallization by dipole polarization of amorphous chains while maintaining crystalline domains with exceptional thermal conductance. This precisely orchestrated hierarchical architecture optimizes thermal conductance by efficient phonon transmission along C–
Baoxi Zhang, Shenglong Rui, Jingjing Liu, Zhanxiang Zhang, Yuan Cheng, Xinghong Zhang   +5 more
wiley   +1 more source

Monte Carlo Simulation on Adiabatic Ensembles and a Genetic Algorithm. [PDF]

Entropy (Basel)
Silva Fernandes FMS.
europepmc   +1 more source