Results 91 to 100 of about 22,920 (247)

Peculiarities of Tlr-2 (Arg753gln) and Tlr-4 (Asp299gly) Polymorphism Prevalence in Patients with Acute Brucelleis and Cardiovascular System Diseases [PDF]

, 2019
Currently, there are single data on the relationship between TLR-2 polymorphisms (Arg753Gln) and TLR-4 (Asp299Gly) polymorphisms and susceptibility to brucellosis.
Huseynov, E. M. (Elchin)
core  

Ratio of Leukotriene E-4 to Exhaled Nitric Oxide and the Therapeutic Response in Children With Exercise-Induced Bronchoconstriction [PDF]

, 2013
Purpose: This study assessed the association between the ratio of leukotriene E-4 (LTE4) to fractional exhaled nitric oxide (FENO) in the response of children with exercise-induced bronchoconstriction (EIB) enrolled in a therapeutic trial with ...
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core   +1 more source

Comparative Risk for Neuropsychiatric Events in Leukotriene Receptor Antagonist vs. Inhaled Corticosteroid in Children With Asthma: A Nationwide Observational Study With a Complementary Analysis Using Natural Language Processing

Pharmacoepidemiology and Drug Safety, Volume 34, Issue 11, November 2025.
ABSTRACT Purpose Leukotriene receptor antagonists (LTRAs) are widely prescribed as controller medications for pediatric asthma. However, there have been increasing concerns about potential neuropsychiatric adverse reactions associated with LTRAs.
Subin Kim, Chang Hoon Han, Junhyuk Chang, Jaehyeong Cho, Kyunguk Jeong, Hamin Kim, Mireu Park, Soo Yeon Kim, Jong Deok Kim, Myung Hyun Sohn, Sooyoung Lee, Rae Woong Park, Seng Chan You, Kyung Won Kim   +13 more
wiley   +1 more source

A Double-Blind Non-inferiority Clinical Study of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Compared with Pranlukast in Patients with Seasonal Allergic Rhinitis

Allergology International, 2008
Background: During the course of development of montelukast, a cysteinyl leukotriene receptor 1 antagonist, for treatment of seasonal allergic rhinitis, a double-blind, non-inferiority study was carried out to evaluate the efficacy and safety of ...
Kimihiro Okubo, Kohtaro Baba
doaj   +1 more source

Bronchodilator Reversibility of Spirometry and Oscillometry Ratios in Severe Refractory Asthma

Clinical &Experimental Allergy, Volume 56, Issue 1, Page 92-94, January 2026.
Robert Greig, Philipp Suter, Rory Chan, Brian Lipworth   +3 more
wiley   +1 more source

Younger Age and Viral Triggers Were Associated With Post‐Infectious Bronchiolitis Obliterans in French Children

Acta Paediatrica, Volume 114, Issue 11, Page 2900-2908, November 2025.
ABSTRACT Aim Post‐infectious bronchiolitis obliterans (PIBO) is a rare but severe chronic paediatric obstructive lung disease, characterised by the obliteration of small airways following severe lower respiratory tract infections. Epidemiological data in Europe remain limited. Methods This multicentre retrospective study examined the characteristics of
Julie Mazenq, Marine Crebassa, Alice Hadchouel, Souad Ghattas, Philippe Reix, Laurianne Coutier, Christophe Marguet, Nadia Nathan, Lisa Giovannini‐Chami, Caroline Thumerelle, François Galode, Marie‐Catherine Renoux, Léa Roditis, Eglantine Hullo, Pierrick Cros, Laurence Weiss, Sébastien Kiefer, Marie Tochon, Brahim Allali, Katia Bessaci Kabouya, Céline Delestrain, Louisa Goumidi, Hortense Petat, Véronique Houdouin, Jean‐Christophe Dubus   +24 more
wiley   +1 more source

Taiwan consensus on pulmonary chronic graft‐versus‐host disease: A joint statement from the Taiwan Society of Blood and Marrow Transplantation (TBMT) and Taiwan Society of Pulmonary and Critical Care Medicine (TSPCCM)

British Journal of Haematology, Volume 207, Issue 5, Page 1815-1831, November 2025.
Summary Pulmonary chronic graft‐versus‐host disease (cGVHD), particularly bronchiolitis obliterans syndrome (BOS), is a severe complication of allogeneic haematopoietic stem cell transplantation (allo‐HSCT) with significant morbidity and mortality.
Xavier Cheng‐Hong Tsai, Zong‐Han Yao, Shu‐Wei Chou, Han‐Chung Hu, Yi‐Chang Liu, Chia‐Hung Chen, Su‐Peng Yeh, Wei‐Chang Huang, Tung‐Liang Lin, Tsung‐Ming Yang, Ching‐Han Lai, Hsin‐Kuo Ko, Yao‐Wen Kuo, Hsao‐Hsun Hsu, Shih‐Lung Cheng, Chi‐Cheng Li, Bor‐Sheng Ko, Hao‐Chien Wang, on behalf of the Taiwan Society of Blood and Marrow Transplantation and Taiwan Society of Pulmonary and Critical Care Medicine   +18 more
wiley   +1 more source

Effects of montelukast on M2-related cytokine and chemokine in M2 macrophages

Journal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Asthma is a chronic airway inflammatory disease mediated by T-helper (Th)2 cells. Montelukast (trade name Singulair) is a cysteinyl leukotriene receptor antagonist used for asthma treatment.
Yi-Ching Lin, Ming-Yii Huang, Min-Sheng Lee, Chong-Chao Hsieh, Hsuan-Fu Kuo, Chang-Hung Kuo, Chih-Hsing Hung   +6 more
doaj   +1 more source

Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]

, 2019
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core   +1 more source

Relationship Between Gender and the Effectiveness of Montelukast: An Italian/Danish Register-Based Retrospective Cohort Study

Frontiers in Pharmacology, 2018
Rationale: Gender-related differences in asthma prevalence, pathophysiology and clinical features induced by sex steroids have been investigated, however, how gender influences response to asthma treatments in routine clinical practice have not yet been ...
Maurizio Sessa, Maurizio Sessa, Annamaria Mascolo, Bruno D'Agostino, Antonio Casciotta, Vincenzo D'Agostino, Fausto De Michele, Mario Polverino, Giuseppe Spaziano, Mikkel Porsborg Andersen, Kristian Kragholm, Kristian Kragholm, Kristian Kragholm, Francesco Rossi, Christian Torp-Pedersen, Christian Torp-Pedersen, Annalisa Capuano   +16 more
doaj   +1 more source