Results 101 to 110 of about 13,200 (163)

The effects of montelukast against amikacin-induced acute renal damage

, 2012
Background and Objectives: The therapeutic and protective effects of montelukast against amikacin-induced acute renal damage were investigated. Material and Methods: 35 Wistar albino female rats were divided into 5 groups as follows: Group I: Control ...
Cinar, K., Ekincioglu, Z., Vardi, N., Dogan, Z., Beytur, A., Kose, E., Ekinci, N.   +6 more
core  

Montelukast alleviates neuroinflammation and improves motor functions in the line 61 model of Parkinson's disease: An exploratory study

Neurotherapeutics
Parkinson's disease (PD) is a neurodegenerative movement disorder of high global burden. Uncertainties regarding its exact etiology have been hindering the development of curative therapies.
Katharina Strempfl, Marco Zattoni, Heike Mrowetz, Michael S. Unger, Nikolaos Schörghofer, Barbara Altendorfer, Jörg Neddens, Stefanie Flunkert, Birgit Hutter-Paier, Yachao He, Johan Wallin, Rodolphe W. Poupardin, Frank Pietrantonio, Nadine Paiement, Horst Zerbe, Thomas Felder, Per Svenningsson, Ludwig Aigner   +17 more
doaj   +1 more source

Risk of neuropsychiatric adverse events associated with montelukast use in children and adolescents: a population-based case-crossover study

BMJ Paediatrics Open
Purpose Montelukast is used extensively in children and adolescents for allergic rhinitis and asthma. However, concerns have been raised regarding the increased risk of neuropsychiatric adverse events (NPAEs) associated with montelukast use.
Ju-Young Shin, Jae Won Kim, Mideum Kim, Min Sook Seo   +3 more
doaj   +1 more source

Effects of montelukast on burn wound healing in a rat model

, 2010
Purpose: Montelukast, a selective cysteinyl leukotriene D(4)-receptor antagonist, is used in the treatment of asthma. In a rat model, our aim was to investigate the effects of montelukast, alone or in combination with topical antibiotics, on local burn ...
Turtay, Muhammet G., Oguzturk, Hakan, Firat, Cemal, Samdanci, Emine, Colak, Cemil, Erbatur, Serkan   +5 more
core   +2 more sources

Efficacy Of Montelukast As A Therapeutic Option In Bronchiolitis [PDF]

OBJECTIVE: To determine the efficacy of Montelukast as a therapeutic option in treating bronchiolitis and establish a relationship between Montelukast and clinical outcomes in our children with acute bronchiolitis.
Iqbal, Amjad, Aslam, Muhammad Shahid, Sabir, Sajjad, Akhtar, Zohaib, Aslam, Sohail, Iqbal, Tahreem   +5 more
core   +1 more source

The Efficacy of Montelukast Monotherapy in Moderate Persistent Asthmatic Children

Iranian Journal of Allergy, Asthma and Immunology, 2009
Although current guidelines place single leukotriene receptor antagonists use as a therapeutic option in mild persistent asthma, there is still uncertainty about its place.
Mahir Igde, Fehim Yasar Anlar
doaj  

Effectiveness of Montelukast in Reducing the Risk of Severe Dengue in Dengue Fever Patients: An Evidence-Based Case Report

Acta Medica Indonesiana
Background: Dengue fever continues to spread worldwide, particularly in tropical regions. Some patients with dengue fever may progress to severe dengue, which is associated with significantly higher morbidity and mortality.
Nicholas Jason Wijaya, Sharifah Shakinah, Leonard Nainggolan, Erni Juwita Nelwan   +3 more
doaj   +4 more sources

Montelukast protects against rotenone-induced neurotoxicity in human neuroblastoma cells through regulation of the p38MAPK signaling pathway

Discover Neuroscience
Cysteinyl leukotriene receptor 1 (CysLTR1) has been implicated in various inflammatory conditions; however, its role in Parkinson’s disease (PD) pathogenesis remains to be explored.
Apurva Chittoda, Shivam Kumar Pandey, Shashikesh Shukla, Shreya Singh, Shad Ahmed, Rakesh Kumar Singh   +5 more
doaj   +1 more source

Neuropsychiatric outcomes after montelukast versus inhaled corticosteroids in pediatric asthma: a pooled birth cohort study. [PDF]

BMC Med
Jiao XF, Ducharme FM, Leal LF, Longo C, Sheehy O, Kaguelidou F, Bérard A.   +6 more
europepmc   +1 more source

Comparative adjuvant therapy to reduce vancomycin-associated nephrotoxicity in an animal model. [PDF]

Antimicrob Agents Chemother
Xiao Y, Teran NS, Hudson CS, Nigo M, Tam VH.   +4 more
europepmc   +1 more source