Results 1 to 10 of about 123,231 (223)
Leukotriene antagonists in dermatology
Indian Journal of Dermatology, 2021 Leukotriene antagonists constitute an important group of drugs in the therapeutic armamentarium of all dermatologists. It has been quite valuable in the management of various types of urticaria and atopic dermatitis. Recently, the role of zileuton in the
Aditya Kumar Bubna
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Педиатрическая фармакология, 2009 The article provides data regarding the clinical efficacy and safety of leukotriene receptor antagonists in treatment of bronchial asthma in children. The only representative of this group that is allowed in Russia for treatment of children over 6 years ...
Yu.G. Levina, L.S. Namazova-Baranova
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Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]
Journal of Occupational Medicine and Toxicology, 2008 Background Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
Groneberg David A +3 more
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Introduction of Leukotriene Receptor Antagonists in Manitoba [PDF]
Canadian Respiratory Journal, 2006 Patient characteristics and prescribing patterns during the introduction of leukotriene receptor antagonists (LTRA) in Manitoba are described using the provincial health database.
C Macie +3 more
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An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection. [PDF]
PLoS ONE, 2013 While tuberculosis susceptibility has historically been ascribed to failed inflammation, it is now known that an excess of leukotriene A4 hydrolase (LTA4H), which catalyzes the final step in leukotriene B4 (LTB4) synthesis, produces a hyperinflammatory ...
David M Tobin +4 more
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Leukotriene Receptor Antagonists and Related Compounds [PDF]
Canadian Respiratory Journal, 1999 Leukotrienes (LTs), lipid mediators of inflammation, have proved to be important biochemicals involved in the symptoms and physiological changes of asthma.
Sally E Wenzel
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Journal of Asthma and Allergy, 2008 Gabriele Di Lorenzo1, Alberto D’Alcamo1, Manfredi Rizzo1, Maria Stefania Leto-Barone1, Claudia Lo Bianco1, Vito Ditta1, Donatella Politi1, Francesco Castello1, Ilenia Pepe1, Gaetana Di Fede2, GiovamBattista Rini11Dipartimento di Medicina ...
Gabriele Di Lorenzo +5 more
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Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source
Leukotrienes, leukotriene receptor antagonists, and rhinitis [PDF]
Allergy, 2000 A series of clinical studies have shown the ef®cacy of leukotriene (LT) receptor antagonists (LTRAs) in the treatment of bronchial asthma (1±6). LTRAs relieve bronchospasm, prevent exercise-induced asthma, and reduce bronchial hyperresponsiveness.
N, Mygind, R, Dahl, H, Bisgaard
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