Results 11 to 20 of about 13,142 (278)

Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]

Journal of Occupational Medicine and Toxicology, 2008
Background Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
Groneberg David A, Staats Petra, Schmidt Rene, Wagner Ulrich   +3 more
doaj   +2 more sources

Introduction of Leukotriene Receptor Antagonists in Manitoba [PDF]

Canadian Respiratory Journal, 2006
Patient characteristics and prescribing patterns during the introduction of leukotriene receptor antagonists (LTRA) in Manitoba are described using the provincial health database.
C Macie, K Wooldrage, J Manfreda, NR Anthonisen   +3 more
doaj   +3 more sources

ASSESSMENT OF EFFICACY OF LEUKOTRIENE RECEPTOR ANTAGONISTS IN THERAPY OF BRONCHIAL ASTHMA IN CHILDREN

Педиатрическая фармакология, 2009
The article provides data regarding the clinical efficacy and safety of leukotriene receptor antagonists in treatment of bronchial asthma in children. The only representative of this group that is allowed in Russia for treatment of children over 6 years ...
Yu.G. Levina, L.S. Namazova-Baranova
doaj   +4 more sources

Leukotriene Receptor Antagonists and Related Compounds [PDF]

Canadian Respiratory Journal, 1999
Leukotrienes (LTs), lipid mediators of inflammation, have proved to be important biochemicals involved in the symptoms and physiological changes of asthma.
Sally E Wenzel
doaj   +2 more sources

Leukotriene receptor antagonists in monotherapy or in combination with antihistamines in the treatment of chronic urticaria: a systematic review

Journal of Asthma and Allergy, 2008
Gabriele Di Lorenzo1, Alberto D’Alcamo1, Manfredi Rizzo1, Maria Stefania Leto-Barone1, Claudia Lo Bianco1, Vito Ditta1, Donatella Politi1, Francesco Castello1, Ilenia Pepe1, Gaetana Di Fede2, GiovamBattista Rini11Dipartimento di Medicina ...
Gabriele Di Lorenzo, Alberto D’Alcamo, Manfredi Rizzo, Maria Stefania Leto-Barone, Claudia Lo Bianco, et al   +5 more
doaj   +1 more source

Update on leukotriene receptor antagonists in preschool children wheezing disorders

Italian Journal of Pediatrics, 2012
Asthma is the most common chronic disease in young children. About 40% of all preschool children regularly wheeze during common cold infections. The heterogeneity of wheezing phenotypes early in life and various anatomical and emotional factors unique to
Montella Silvia, Maglione Marco, De Stefano Sara, Manna Angelo, Di Giorgio Angela, Santamaria Francesca   +5 more
doaj   +2 more sources

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Circulating leukotriene b4 identifies respiratory complications after trauma [PDF]

, 2012
Background. Leukotriene B4 (LTB4), a proinflammatory lipid mediator correlates well with the acute phase of Acute Respiratory Distress Syndrome (ARDS). Therefore, LTB4-levels were investigated to determine whether they might be a useful clinical marker ...
Henrich, Dirk, Geiger, Emanuel Valentin, Lehnert, Mark, Marzi, Ingo, Emanuel V. Geiger, Ingo Marzi, Dirk Henrich, Birgit Auner, Auner, Birgit, Borna Relja, Relja, Borna, Mark Lehnert   +11 more
core   +1 more source

Tolerability profiles of leukotriene receptor antagonists and long-acting beta2-adrenoceptor agonists in combination with inhaled corticosteroids for treatment of asthma: a review [PDF]

, 2007
Inhaled corticosteroids, long-acting beta2-adrenoceptor agonists, and leukotriene receptor antagonists are widely used for treatment of asthma. Inhaled corticosteroids are recommended as first-line therapy, whereas long-acting beta2-adrenoceptor agonists
FORNAI, MATTEO, ANTONIOLI, LUCA, DEL TACCA M., TUCCORI M, BLANDIZZI, CORRADO, COLUCCI R, PASQUALETTI G   +6 more
core   +2 more sources