Results 11 to 20 of about 123,231 (223)

New and promising type of leukotriene B4 (LTB4) antagonists based on the 1,4-benzodioxine structure [PDF]

, 2023
New leukotriene B4 (LTB4) antagonists have been synthesized that can be considered as potential anti-inflammatory drugs. Structures containing the dioxygenated nucleus of 1,4-benzodioxine constitute a potential group of leukotriene B4 (LTB4) antagonists.
Bouissane, Latifa, Khouili, Mostafa, Guillaumet, Gérald, Coudert, Gérard, Pujol Dilmé, M. Dolors   +4 more
core   +2 more sources

Leukotriene Receptor Antagonists [PDF]

Seminars in Respiratory and Critical Care Medicine, 2002
In the past decade, heightened emphasis has been placed on the importance of inflammation in the pathogenesis of asthma. Although corticosteroids have remained the primary anti-inflammatory agents in the management of the persistent asthmatic, new classes of drugs have recently been added.
Marzena E, Krawiec, Nizar J, Jarjour
openaire   +2 more sources

Comparative Study to Assess Clinical Efficacy of Leukotriene Receptor Antagonist and Antihistamines in the Treatment of Allergic Rhinitis

Bengal Journal of Otolaryngology and Head Neck Surgery, 2017
Introduction Pharmacologic treatment  options for allergic rhinitis include intranasal corticosteroids, oral and topical antihistamines, decongestants, intranasal cromolyn, intranasal anticholinergics and leukotriene receptor antagonists.
Gurpreet Kaur, Rachna Dhingra, Manjinder Singh   +2 more
doaj   +3 more sources

Tolerability profiles of leukotriene receptor antagonists and long-acting beta2-adrenoceptor agonists in combination with inhaled corticosteroids for treatment of asthma: a review [PDF]

, 2007
Inhaled corticosteroids, long-acting beta2-adrenoceptor agonists, and leukotriene receptor antagonists are widely used for treatment of asthma. Inhaled corticosteroids are recommended as first-line therapy, whereas long-acting beta2-adrenoceptor agonists
COLUCCI, ROCCHINA LUCIA, ANTONIOLI L, FORNAI F, BLANDIZZI C, DEL TACCA M., DEL TACCA M, TUCCORI M, COLUCCI R, PASQUALETTI G, FORNAI M, M. Del Tacca, L. Antonioli, G. Pasqualetti, FORNAI, MATTEO, C. Blandizzi, ANTONIOLI, LUCA, M. Tuccori, R. Colucci, M. Fornai, BLANDIZZI, CORRADO   +19 more
core   +2 more sources

A pragmatic single-blind randomised controlled trial and economic evaluation of the use of leukotriene receptor antagonists in primary care at steps 2 and 3 of the national asthma guidelines (ELEVATE study)

Health Technology Assessment, 2011
Objectives: To evaluate, under real-life practice conditions in UK primary care, asthma control and cost-effectiveness of commencing therapy with leukotriene antagonists compared with inhaled corticosteroids (ICSs) as initial controller therapy and ...
D Price, S Musgrave, E Wilson, E Sims, L Shepstone, A Blyth, J Murdoch, M Mugford, E Juniper, J Ayres, S Wolfe, D Freeman, A Lipp, R Gilbert, I Harvey   +14 more
doaj   +1 more source

Montelukast and Coronavirus Disease 2019: A Scoping Review

Iranian Journal of Allergy, Asthma and Immunology, 2021
Coronavirus disease 2019 (COVID-19) is an emerging worldwide issue, that has affected a large number of people around the world. So far, many studies have aimed to develop a therapeutic approach against COVID-19.
Niusha Sharifinejad, Samin Sharafian, Sana Salekmoghadam, Marzieh Tavakol, Mostafa Qorbani   +4 more
doaj   +1 more source

The Use of Leukotriene Antagonists in the Treatment of Capsular Contracture in Breast Augmentation Patients

, 2021
Purpose The purpose of this article is to review the off-label utilization of leukotriene antagonists in breast augmentation patients and the effect they may have on the prophylaxis or treatment of capsular contracture.
Brown, Kristin M
core   +1 more source

Circulating leukotriene b4 identifies respiratory complications after trauma [PDF]

, 2012
Background. Leukotriene B4 (LTB4), a proinflammatory lipid mediator correlates well with the acute phase of Acute Respiratory Distress Syndrome (ARDS). Therefore, LTB4-levels were investigated to determine whether they might be a useful clinical marker ...
Henrich, Dirk, Geiger, Emanuel Valentin, Lehnert, Mark, Marzi, Ingo, Emanuel V. Geiger, Ingo Marzi, Dirk Henrich, Birgit Auner, Auner, Birgit, Borna Relja, Relja, Borna, Mark Lehnert   +11 more
core   +1 more source

Use of Leukotriene-Receptor Antagonists During Pregnancy and Risk of Neuropsychiatric Events in Offspring

, 2023
[[abstract]]Leukotriene-receptor antagonists (LTRAs) are a class of medications used for treating allergic airway diseases, including asthma and allergic rhinitis.
Tsai, HJ;Wu, CS;Chang, YC;Yao, TC, Tsai, Hui-Ju, Wu, Chi-Shin, Hui-Ju Tsai, Yen-Chen Chang, Yao, Tsung-Chieh, Chi-Shin Wu, Tsung-Chieh Yao, Chang, Yen-Chen   +8 more
core   +1 more source

Leukotrienes and leukotriene modifiers in pediatric allergic diseases [PDF]

, 2014
Leukotrienes are potent pro-inflammatory lipid mediators derived from arachidonic acid through several enzymatic pathways. They have an essential role in allergic inflammation, where they induce bronchoconstriction, airway edema, and chemotaxis of the ...
El-Ghoneimy, D H, El-Sayed, Z A
core   +1 more source