Results 21 to 30 of about 123,231 (223)

Omalizumab: opción terapéutica para la urticaria crónica espontánea de difícil control con vasculitis asociada, reporte de tres casos

Biomédica: revista del Instituto Nacional de Salud, 2013
Introducción. Aproximadamente el 50 % de los casos de urticaria crónica no mejoran adecuadamente con las dosis convencionales de antihistamínicos, por lo cual se han planteado múltiples opciones terapéuticas, entre las cuales el omalizumab es una ...
Libia Susana Diez, Liliana María Tamayo, Ricardo Cardona   +2 more
doaj   +1 more source

Effect of a Single Dose Montelukast Sodium on Methacholine Chloride PC20

Canadian Respiratory Journal, 2005
BACKGROUND: It is currently recommended that leukotriene modifiers (receptor antagonists and synthesis inhibitors) be withheld for a minimum of 24 h before direct bronchoprovocation testing, but there is little evidence to support this recommendation.
Beth E Davis, Donald W Cockcroft
doaj   +1 more source

Leukotriene receptor antagonists for eczema [PDF]

Cochrane Database of Systematic Reviews, 2018
Eczema is a common, chronic, inflammatory skin condition that is frequently associated with atopic conditions, including asthma. Leukotriene receptor antagonists (LTRAs) have a corticosteroid-sparing role in asthma, but their role in eczema remains controversial.
Leila, Ferguson, Masaki, Futamura, Efstratios, Vakirlis, Reiji, Kojima, Hatoko, Sasaki, Amanda, Roberts, Rintaro, Mori   +6 more
openaire   +2 more sources

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

Nature Communications, 2019
Cysteinyl leukotriene G protein-coupled receptors CysLT1 and CysLT2 regulate pro-inflammatory responses associated with allergic disorders. Here, authors describe four crystal structures of CysLT2R in complex with three dual CysLT1R/CysLT2R antagonists ...
Anastasiia Gusach, Aleksandra Luginina, Egor Marin, Rebecca L. Brouillette, Élie Besserer-Offroy, Jean-Michel Longpré, Andrii Ishchenko, Petr Popov, Nilkanth Patel, Taku Fujimoto, Toru Maruyama, Benjamin Stauch, Margarita Ergasheva, Daria Romanovskaia, Anastasiia Stepko, Kirill Kovalev, Mikhail Shevtsov, Valentin Gordeliy, Gye Won Han, Vsevolod Katritch, Valentin Borshchevskiy, Philippe Sarret, Alexey Mishin, Vadim Cherezov   +23 more
doaj   +1 more source

Treatment of refractory chronic urticaria

Indian Journal of Dermatology, 2015
Chronic spontaneous urticaria is a distressing disease encountered frequently in clinical practice. The current mainstay of therapy is the use of second-generation, non-sedating antihistamines.
Aayushi Mehta, Kiran Godse, Sharmila Patil, Nitin Nadkarni, Manjyot Gautam   +4 more
doaj   +1 more source

Cross roads between Pulmonology and Psychiatry

Telangana Journal of Psychiatry, 2017
Leukotriene receptor antagonists (Montelukast) has been used for many years in the treatment of asthma in both acute and chronic stages. It is considered safe and is widely used in pediatric age group as well as adults.
M Ajit, K Lokesh Kumar, K Sandeep Krishnamurthy   +2 more
doaj   +1 more source

The beneficial effects of Montelukast against 2,3,7,8-tetrachlorodibenzo- p -dioxin toxicity in female reproductive system in rats [PDF]

Acta Cirúrgica Brasileira, 2016
PURPOSE: To determine the toxic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on reproductive system and the beneficial effects of Montelukast (ML) with histological and biochemical analysis.
Rauf Melekoglu, Osman Ciftci, Aslı Cetin, Nese Basak, Ebru Celik   +4 more
doaj   +1 more source

Aspirin-Exacerbated Asthma

Allergy, Asthma & Clinical Immunology, 2008
This review focuses on aspirin-exacerbated asthma (AEA). The review includes historical perspective of aspirin, prevalence, pathogenesis, clinical features and treatment of AEA.
Varghese Mathew, Lockey Richard F
doaj   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Comparison of Oral Montelukast and Intranasal Fluticasone in Patients with Asthma and Allergic Rhinitis [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Even though the links between upper and lower airway had been of interest to clinicians since long back, it has not attracted the attention of the researchers till recent past.
Apar Jindal, Subramanian Suriyan, Suresh Sagadevan, Meenakshi Narasimhan, Aruna Shanmuganathan, Viswambhar Vallabhaneni, Ragulan Rajalingam   +6 more
doaj   +1 more source