Results 211 to 220 of about 1,494,073 (261)
Advanced Science, EarlyView.AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang +19 more
wiley +1 more source
Advanced Science, EarlyView.Astrocytic SCTR modulates depressive‐related phenotypes via AMPKα1, whereas lowered Mt1 blunts Megalin‐dependent AMPKα2 signaling in serotonergic neurons. Diminished AMPKα2 hinders KAT7 nuclear translocation, curtails KAT7 occupancy and H4K8ac at the Foxc2 promoter, and represses Foxc2 transcription, revealing cell‐type‐specific AMPK‐linked epigenetic ...
Fantao Meng +15 more
wiley +1 more source
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Continuum, 2021
This comprehensive review of mood disorders brings together the past and current literature on the diagnosis, evaluation, and treatment of the depressive and bipolar disorders. It highlights the primary mood disorders and secondary neurologic causes of mood disorders that are commonly encountered in a clinical setting.
Shae, Datta +2 more
openaire +2 more sources
This comprehensive review of mood disorders brings together the past and current literature on the diagnosis, evaluation, and treatment of the depressive and bipolar disorders. It highlights the primary mood disorders and secondary neurologic causes of mood disorders that are commonly encountered in a clinical setting.
Shae, Datta +2 more
openaire +2 more sources
Neuroimaging Clinics of North America, 2007
Despite the prevalence of the mood disorders, the underlying neuropathology is still poorly understood. This article describes abnormalities in brain activation that have been reported in neuroimaging studies of patients with depression and bipolar illness.
Deborah A, Yurgelun-Todd +2 more
openaire +2 more sources
Despite the prevalence of the mood disorders, the underlying neuropathology is still poorly understood. This article describes abnormalities in brain activation that have been reported in neuroimaging studies of patients with depression and bipolar illness.
Deborah A, Yurgelun-Todd +2 more
openaire +2 more sources
Continuum, 2018
This article discusses the prevalence of the major mood disorders (major depressive disorder and bipolar disorder) in the community and within neurologic settings, articulates the steps taken to make a diagnosis of major depressive disorder or bipolar disorder, and reviews old and newer treatment options with proven efficacy for the treatment of these ...
Jeffrey, Rakofsky, Mark, Rapaport
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This article discusses the prevalence of the major mood disorders (major depressive disorder and bipolar disorder) in the community and within neurologic settings, articulates the steps taken to make a diagnosis of major depressive disorder or bipolar disorder, and reviews old and newer treatment options with proven efficacy for the treatment of these ...
Jeffrey, Rakofsky, Mark, Rapaport
openaire +2 more sources
Asian Journal of Psychiatry, 2012
Mood disorders are disorders that have a disturbance in mood as the predominant feature. They are common psychiatric disorders and are associated with significant distress and functional impairment. As the theory of mood disorders is based on the philosophy of mind/body dichotomy in the West, it contradicts the holistic tradition of medicine in the ...
Albert, Yeung, Doris, Chang
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Mood disorders are disorders that have a disturbance in mood as the predominant feature. They are common psychiatric disorders and are associated with significant distress and functional impairment. As the theory of mood disorders is based on the philosophy of mind/body dichotomy in the West, it contradicts the holistic tradition of medicine in the ...
Albert, Yeung, Doris, Chang
openaire +2 more sources
Medical Clinics of North America, 2006
Mood disorders in the elderly are a growing source of morbidity and mortality. Unfortunately, mood disorders in later life frequently are not diagnosed and treated. Appropriate, prompt diagnosis and treatment of late-life mood disorders can significantly improve the quality of life of patients and families and may prove life saving.
Mehret, Gebretsadik +2 more
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Mood disorders in the elderly are a growing source of morbidity and mortality. Unfortunately, mood disorders in later life frequently are not diagnosed and treated. Appropriate, prompt diagnosis and treatment of late-life mood disorders can significantly improve the quality of life of patients and families and may prove life saving.
Mehret, Gebretsadik +2 more
openaire +2 more sources
Allopregnanolone and mood disorders
Progress in Neurobiology, 2014Certain women experience negative mood symptoms during the menstrual cycle and progesterone addition in estrogen treatments. In women with PMDD increased negative mood symptoms related to allopregnanolone increase during the luteal phase of ovulatory menstrual cycles. In anovulatory cycles no symptom or sex steroid increase occurs.
T, Bäckström +10 more
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Endocrinology and Metabolism Clinics of North America, 1997
Studies of depressive symptoms in menopausal women indicate that menopause is not associated with increased rates of depression, although mild mood and anxiety symptoms may occur in the few years prior to menopause. Women with previous affective disorders that are cyclic or that are associated with reproductive events may be at increased risk for ...
T, Pearlstein, K, Rosen, A B, Stone
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Studies of depressive symptoms in menopausal women indicate that menopause is not associated with increased rates of depression, although mild mood and anxiety symptoms may occur in the few years prior to menopause. Women with previous affective disorders that are cyclic or that are associated with reproductive events may be at increased risk for ...
T, Pearlstein, K, Rosen, A B, Stone
openaire +2 more sources