Results 271 to 280 of about 3,766,461 (388)

88.3 Impulsivity, Inattention, and Hyperactivity and Comorbid Mood Dysregulation in Intellectual and Developmental Disorders: A Challenging Intersection [PDF]

Ernest V. Pedapati
openalex   +1 more source

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

Temperament correlates of stigma resistance among patients with mood disorders: a cross-sectional study. [PDF]

Front Psychiatry
Urbani R, Chatton A, Jermann F, Favre S, Richard-Lepouriel H.   +4 more
europepmc   +1 more source

Early risk factors for metabolic dysfunction in young people with major mood disorders: Longitudinal path analysis of a prospective birth cohort using structural equation modelling [PDF]

Sarah McKenna, Mathew Varidel, Mirim Shin, J.W. Carpenter, Emiliana Tonini, Jacob J. Crouse, Elizabeth Scott, Abdullah Al Mamun, Jake M. Najman, James G. Scott, Ian B. Hickie   +10 more
openalex   +1 more source

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

Advanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim, Hanjun Hwangbo, ByungJoon Choi, Dogeon Yoon, GeunHyung Kim   +4 more
wiley   +1 more source

Investigating the Associated Factors of Mood Disorders and Fatigue in Multiple Sclerosis Patients With Cognitive Impairment: A Cross-Sectional Study. [PDF]

Health Sci Rep
Sedighi B, Afshar PJ, Jafari S.
europepmc   +1 more source

The Role of Mood Stabilizers and Antipsychotics in the Treatment of Borderline Personality Disorder [PDF]

J. Fonseca Barbosa, D. M. Silva, B. Leal, A. Lourenço, Aline Nunes, M. A. Silva, C. Oliveira, M. Nascimento   +7 more
openalex   +1 more source

The Circadian Transcription Factor CLOCK Modulates Oxidative Stress Resistance via the ACHL–Relish Axis in Drosophila

Advanced Science, EarlyView.
This study identifies the circadian transcription factor CLOCK (CLK) as a key regulator of oxidative stress resistance in fruit flies. CLK controls immune responses by driving rhythmic transcription of an RNA‐binding protein‐Achilles (ACHL) in the fly brain, which post‐transcriptionally represses the NF‐κB homolog Relish, limiting immune activation and
Xu Liu, Jiajia Fang, Dawei Cheng, Wei Luan, Yan Lv, Wen Hu, Lei Pan, Yong Zhang   +7 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source