Results 91 to 100 of about 800,782 (389)
Religiosity, morality and hardworking: Relationship models on diversity of religion in Indonesia [PDF]
Journal of Studies in Social Sciences and Humanities, 2022 This study aims to examine the model of religious relations, morality, and hard work among young people with the diversity of religions in Indonesia. Religion is valued by extrinsic and intrinsic religious orientations.
Dorothea Wahyu Ariani
doaj
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Untangling Partnership and Domination Morality
Interdisciplinary Journal of Partnership Studies, 2015 Riane Eisler’s (1987) cultural transformation theory is an effective framework for understanding many of the constructs that shape society. This article uses Eisler’s theory to explain the formation of morality and the construction of conscience.
David Loye
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Playing Around With Morality: Introducing the Special Issue on “Morality Play” [PDF]
, 2019 This special issue of Games and Culture focuses on the intersection between video games and ethics. This introduction briefly sets out the key research questions in the research field and identifies trends in the articles included in ...
Formosa, Paul +2 more
core
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A Dual Mechanism of Cognition and Emotion in Processing Moral-Vertical Metaphors
Frontiers in Psychology, 2018 A moral concept involves two main factors: moral cognition (indicated by morality) and emotion (indicated by emotionality). The cognitive mechanism underlying moral metaphors on the vertical dimension (e.g., moral-up, immoral-down) was investigated in ...
Dongxue Zhai +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
A Theory of Moral Persistence: Crypto-Morality and Political Legitimacy [PDF]
Why, how, and under what conditions do moral beliefs persist despite institutional pressure for change? Why do the powerful often fail to promote the morality of their authority?
Avner Greif, Steven Tadelis
core
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source