Results 91 to 100 of about 762,520 (384)

Text-based inference of moral sentiment change [PDF]

open access: yesarXiv, 2020
We present a text-based framework for investigating moral sentiment change of the public via longitudinal corpora. Our framework is based on the premise that language use can inform people's moral perception toward right or wrong, and we build our methodology by exploring moral biases learned from diachronic word embeddings.
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Neurofunctional Prudence and Morality: A Philosophical Theory [PDF]

open access: yes, 2020
This book outlines a unified theory of prudence and morality that merges a wide variety of findings in behavioral neuroscience with philosophically sophisticated normative theorizing.
Arvan, Marcus
core  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Principlism: bioethics as procedure? [PDF]

open access: yes, 2012
In their book Principles of Biomedical Ethics, Tom Beauchamp and James Childress offer an account of bioethics, called “Principlism”, by way of specifying and balancing four clusters of principles.2 These principles are found, as the author state, in a ...
Pereira Sáez, Carolina
core  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Understanding Catholic morality [PDF]

open access: yes, 1999
Willems, Elizabeth. Understanding Catholic morality.
O\u27Connor, Thomas St. James
core   +1 more source

A Dual Mechanism of Cognition and Emotion in Processing Moral-Vertical Metaphors

open access: yesFrontiers in Psychology, 2018
A moral concept involves two main factors: moral cognition (indicated by morality) and emotion (indicated by emotionality). The cognitive mechanism underlying moral metaphors on the vertical dimension (e.g., moral-up, immoral-down) was investigated in ...
Dongxue Zhai   +4 more
doaj   +1 more source

Religiosity, morality and hardworking: Relationship models on diversity of religion in Indonesia [PDF]

open access: yesJournal of Studies in Social Sciences and Humanities, 2022
This study aims to examine the model of religious relations, morality, and hard work among young people with the diversity of religions in Indonesia. Religion is valued by extrinsic and intrinsic religious orientations.
Dorothea Wahyu Ariani
doaj  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

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