Results 141 to 150 of about 762,520 (384)
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
The correlation between human capital and morality and its effect on economic performance : theory and evidence [PDF]
This paper incorporates morality -- defined as lower utility from consuming goods obtained through appropriative rather than productive activities -- into a simple static general equilibrium model in which agents choose whether to be producers or ...
Balan, David J., Knack, Stephen
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Docility and “through doing” morality: An alternative approach to ethics [PDF]
In this paper, we aim at presenting the distributed morality approach as it can be described by the docility model of social interactions. The proposition “morality is a matter of social interaction” constitutes our starting point. We aim at pointing out
Bardone Emanuele +2 more
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Carol Ann Duffy’s Everyman (2015), A Contemporary Morality Play
Theatre Academy, 2023 Morality is a particular system that regulates human relations, and in this respect, moral behaviour is one of the most necessary attributes of humankind as a social being.
Esma Seçen Hınıslıoğlu
doaj
RELIGION AND MORALITY IN LATIN OF THE HIGH SCHOOL [PDF]
, 1912 Frank B. Meyer
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
In recent debates, morality or social norms have been proposed as an instrument to reduce conflict behavior. As the argument goes, moral people will not engage in socially not-tolerated behavior or, less so than amoral people.
Dorothee Schmidt
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