Results 151 to 160 of about 707,954 (344)
„Must Writers Be Moral?“*: Interdisziplinäre Perspektiven auf Morality Clauses im Literaturbetrieb
, 2023 Caroline Koegler +3 more
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Editors' Note: Morality Battles: Looking Back to Look Forward [PDF]
, 2006 Valerie Jenness +2 more
openalex +1 more source
What is become of the rights of men? : are you the only men who have rights? ; moral contractarianism and the legitimation of universal human rights [PDF]
, 2012 In this article I advance an account of human rights as individual claims that can be justified within the conceptual framework of social contract theories. The contractarian approach at issue here aims, initially, at a justification of morality at large,
Araujo, Marcelo de
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Delineating The Moral Domain in Moral Psychology [PDF]
, 2014 The aim of this paper is to review current debate about the moral domain in the moral psychological literature. There is some vagueness in respect to the usage of the very concept of ‘morality’.
Berniūnas, Renatas
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Practical Christianity: Religion in Jane Austen\u27s Novels [PDF]
, 2017 A beloved English novelist of the late eighteenth century, Jane Austen captures the attention and emotion of readers through timeless insights into the inner workings of the human heart as characters navigate society, family life, and love.
Toal, Erin R
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source