Results 71 to 80 of about 800,782 (389)
Law and morality in contemporary philosophy of law [PDF]
In this paper, author tries to analyze complex character of the relation between law and morality in contemporary law philosophy. There are three approaches to the issue of relation between law and morality: natural law theory (identity thesis ...
Stanković Dejan Vuk
doaj +1 more source
The Function of Normative Process‐Requirements [PDF]
This paper discusses whether rationality, morality or prudence impose process‐requirements upon us. It has been argued that process‐requirements fulfil two essential functions within a system of rational, moral or prudential requirements. These functions
Fink, Julian
core +1 more source
Moral Hybrids, Moral Relevance and Moral Particularism
Some of Jonathan Dancy's strongest arguments in support of moral particularism depend crucially upon the distinction he draws between three different kinds of relevance relations -- favourers, intensifiers and enablers. In this paper I generalize certain features of Dancy's account of the different roles that premises can play in moral argumentation ...
openaire +5 more sources
The Morality of Moral Education
The Background - Moral Education as the Traditional Source of Personal Development. One of the abiding interests of moral philosophy is how some measure of competence at existence can not only be attained, but attained to an excellent degree. The idea that man is born imperfect but may so order his life that he approaches a more complete state of ...
Symes, C. T. +2 more
openaire +4 more sources
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Understanding Catholic morality [PDF]
Willems, Elizabeth. Understanding Catholic morality.
O\u27Connor, Thomas St. James
core +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
The Community of Nursing: Moral Friends, Moral Strangers, Moral Family [PDF]
Unlike bioethicists who contend that there is a morality common to all, H. Tristan Engelhardt (1996) argues that, in a pluralistic secular society, any morality that does exist is loosely connected, lacks substantive moral content, is based on the ...
Laabs, Carolyn A.
core +1 more source
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source

