Results 71 to 80 of about 785,945 (409)
The Morality of Moral Education
The Background - Moral Education as the Traditional Source of Personal Development. One of the abiding interests of moral philosophy is how some measure of competence at existence can not only be attained, but attained to an excellent degree. The idea that man is born imperfect but may so order his life that he approaches a more complete state of ...
Symes, C. T.+2 more
openaire +4 more sources
Проблема дослідження моральності в когнітивній парадигмі. (The problem of research morality in cognitive paradigm.) [PDF]
У статті піднімається проблема дослідження моральності в сучасній когнітивній психології. Описуються три шляхи формування моральності – через страх покарання, емпатійний та рефлексивний.
Матласевич , О. В. (О. Matlasevych)
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Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Moral Hybrids, Moral Relevance and Moral Particularism
Some of Jonathan Dancy's strongest arguments in support of moral particularism depend crucially upon the distinction he draws between three different kinds of relevance relations -- favourers, intensifiers and enablers. In this paper I generalize certain features of Dancy's account of the different roles that premises can play in moral argumentation ...
openaire +5 more sources
Reflections on morality in Renaissance thought [PDF]
We can read about the morality of that time in works by authors who describe or criticize the conduct and activity of the members of those classes taking the lead in the morality of that time.
Gluchman, Vasil
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This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
Principlism: bioethics as procedure? [PDF]
In their book Principles of Biomedical Ethics, Tom Beauchamp and James Childress offer an account of bioethics, called “Principlism”, by way of specifying and balancing four clusters of principles.2 These principles are found, as the author state, in a ...
Pereira Sáez, Carolina
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Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
The Function of Normative Process‐Requirements [PDF]
This paper discusses whether rationality, morality or prudence impose process‐requirements upon us. It has been argued that process‐requirements fulfil two essential functions within a system of rational, moral or prudential requirements. These functions
Fink, Julian
core +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source