Results 51 to 60 of about 618 (132)

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, Volume 10, Issue 3, Page 199-218, June 2026.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Bridging Rare to Common Diseases: Precision Medicine and the Transforming Landscape of Pediatric Allergy and Immunology

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
This graphical abstract demonstrates a “rare‐to‐common” translational pipeline. Insights from rare monogenic conditions reveal key mechanisms of immune dysregulation. This knowledge informs the understanding of polygenic common allergic diseases, which share overlapping pathogenic pathways.
Riccardo Castagnoli, Martina Votto, Ivan Taietti, Maria Isabel Delgado‐Dolset, Rubén Fernández‐Santamaría, Martha Jimenez Freites, Mattia Giovannini, Mark Kačar, Aspasia Karavelia, Janice Layhadi, Urszula Radzikowska, Cezmi A. Akdis, Mubeccel Akdis, Marketa Bloomfield, Francesco Cinetto, Antoine Deschildre, Jonathan Hourihane, Susanne Lau, Antonio Nieto‐Garcia, Ismail Ogulur, Liam O'Mahony, Mohamed Shamji, Milena Sokolowska, Maria Jose Torres, Sophia Tsabouri, Philippe Eigenmann, on behalf of the EAACI‐Clemens von Pirquet Foundation   +26 more
wiley   +1 more source

Staphylococcus aureus and Staphylococcus lugdunensis Act in Concert to Disrupt the Nasal Epithelial Barrier

Clinical and Translational Allergy, Volume 16, Issue 5, May 2026.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) pathophysiology and its link to microbiome is an area of ongoing investigation. Certain pathogens, in particular Staphylococcus aureus described to contribute to recalcitrant CRS. In addition, different species of coagulase negative staphylococci (CoNS) are frequently isolated from the sinonasal cavity
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Gohar Shaghayegh, Isabella Burdon, Emma F. Barry, Kevin Aaron Fenix, P. J. Wormald, Alkis J. Psaltis, Sarah Vreugde   +9 more
wiley   +1 more source

The Rho GTPase signaling pathway modulates Moraxella catarrhalis invasion into human respiratory epithelial cells by regulating actin polymerization

Frontiers in Immunology
Moraxella catarrhalis invasion of host respiratory epithelial cells is a critical mechanism driving acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Although previous studies have extensively demonstrated that dynamic changes in the
Ruirui Ma, Ruirui Ma, Guixue Cheng, Yun Wu, Jiawei Chen, Rongqi Lu, Yali Liu   +6 more
doaj   +1 more source

Differential gene expression of Moraxella catarrhalis upon exposure to human serum

Genomics Data, 2014
The complement system is an important part of the innate defense against invading pathogens (Blom et al., 2009; [1]). The ability to resist complement-mediated killing is considered to be an important virulence trait for the human-restricted respiratory ...
Stefan P.W. de Vries, Hester J. Bootsma
doaj   +1 more source

Molecular Epidemiological Characterization of Respiratory Isolates of Moraxella catarrhalis in a Pediatric Intensive Care Unit

Canadian Journal of Infectious Diseases, 1992
A perceived increase in the number of isolates of Moraxella catarrhalis from the respiratory secretions of patients intubated in the pediatric intensive care unit prompted a review of the clinical profiles of such patients and restriction enzyme analysis
Anne G Matlow, Donald E Low, Gideon Paret, Scott Jarrett, Desmond Bohn, Geoffrey Barker, Jean Boulanger, E Lee Ford-Jones   +7 more
doaj   +1 more source

Moraxella Catarrhalis: A Threat For Hospitalized Patients

RADS Journal of Biological Research & Applied Science, 2016
Over the past two decades Branhamella catarrhalis (now known as Moraxella catarrhalis) has come out as a major pathogenic bacteria in humans. Different researches have uncovered its association in respiratory tract infections (e.g., otitis media ...
Maha Jamil, Naheed Afshan
doaj  

Antibacterial Activity of Polyoxometalates Against Moraxella catarrhalis

Frontiers in Chemistry, 2018
The antibacterial activity of 29 different polyoxometalates (POMs) against Moraxella catarrhalis was investigated by determination of the minimum inhibitory concentration (MIC).
Nadiia I. Gumerova, Emir Al-Sayed, Lukáš Krivosudský, Hana Čipčić-Paljetak, Donatella Verbanac, Annette Rompel   +5 more
doaj   +1 more source

Pathogenicity and Bro gene typing of pediatric lower respiratory tract infections with Moraxella catarrhalis in Southwest Shandong, China

Scientific Reports
To investigate the etiology and clinical characteristics of Moraxella catarrhalis infections in the lower respiratory tract among pediatric patients in southwestern Shandong Province, China.
Yuhan Xiang, Jian Shi, Liang Han, Chengfan Yang, Shuhua Lu   +4 more
doaj   +1 more source

Moraxella nonliquefaciens and M. osloensis Are Important Moraxella Species That Cause Ocular Infections

Microorganisms, 2019
Moraxella is an ocular bacterial pathogen isolated in cases of keratitis, conjunctivitis, and endophthalmitis. Gram-negative brick-shaped diplobacilli from ocular specimens, and slow growth in culture, are early indications of Moraxella ocular infection;
Samantha J. LaCroce, Mollie N. Wilson, John E. Romanowski, Jeffrey D. Newman, Vishal Jhanji, Robert M. Q. Shanks, Regis P. Kowalski   +6 more
doaj   +1 more source