Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity [PDF]
, 2003 We initially performed a mutation screen of the coding region of the MC4R in 808 extremely obese children and adolescents and 327 underweight or normal-weight controls allowing for a case-control study.
Sarah Hohmann +24 more
core +1 more source
Birth Outcomes of Maternal Morbid Obesity [PDF]
, 2020 Background: The prevalence of pregnancy with morbid obesity has increased in the last decade which caused complications for both the mother and fetus. The aim of this study was to find out the birth outcomes of pregnant women with morbid obesity who gave
Agus Sulistyono, - +3 more
core +1 more source
Gastrointestinal Symptoms in Morbid Obesity [PDF]
Frontiers in Medicine, 2014 Several reports have shown an increased prevalence of gastrointestinal (GI) symptoms in obese subjects in community-based studies. To better understand the role of the GI tract in obesity, and because there are limited clinic-based studies, we documented the prevalence of upper and lower GI symptoms in morbidly obese individuals in a clinic setting.The
Huseini, Mustafa +8 more
openaire +3 more sources
Childhood obesity is associated with shorter leukocyte telomere length [PDF]
, 2011 CONTEXT: Obesity in adults is associated with shorter mean leukocyte telomere length (LTL), a marker of biological age that is also associated with age-related conditions including cardiovascular disease and type 2 diabetes. However, studies of childhood
Meyre, D +17 more
core +1 more source
, 2022 This study aimed to investigate and compare the adherence of patients treated for morbid obesity living in Poland and Germany. Methods: A cross-sectional international multicenter survey design was adopted.
Ratajczak, Piotr +27 more
core +1 more source
General practitioners’ beliefs about obesity and their decision to treat [PDF]
, 2013 The current study explored the relationships between GPs‟ beliefs about the cause of obesity and treatment choices. Participants (n = 81) responded to two sets of materials; vignettes featuring obese patients in which the grade and cause of obesity were ...
Hartley, Nicholas Terry
core +6 more sources
The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation [PDF]
, 2009 Objectives: to assess the clinical effectiveness and cost-effectiveness of bariatric surgery for obesity.Data sources: seventeen electronic databases were searched [MEDLINE; EMBASE; PreMedline In-Process & Other Non-Indexed Citations; The Cochrane ...
Colquitt, JL +23 more
core +1 more source
BMC Gastroenterology, 2019 Background Irritable bowel syndrome (IBS) is prevalent in patients with morbid obesity. After Roux-en-Y gastric bypass (RYGB) chronic abdominal pain is common, however the etiology is largely unknown. We aimed to study the change in the prevalence of IBS-
Ingvild Kristine Blom-Høgestøl +7 more
doaj +1 more source
Abdominal pain and symptoms before and after Roux‐en‐Y gastric bypass
BJS Open, 2019 Background Despite increased emphasis on patient‐reported outcomes, few studies have focused on abdominal pain symptoms before and after Roux‐en‐Y gastric bypass (RYGB).
M. Chahal‐Kummen +5 more
doaj +1 more source
Adjusting for reverse causation to estimate the effect of obesity on mortality after incident heart failure in the Atherosclerosis Risk in Communities (ARIC) study [PDF]
Epidemiology and Health, 2016 OBJECTIVES: The lower mortality rate of obese patients with heart failure (HF) has been partly attributed to reverse causation bias due to weight loss caused by disease.
Maryam Shakiba +4 more
doaj +1 more source