Results 51 to 60 of about 931,716 (345)
European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
BJS (British Journal of Surgery), EarlyView., 2020 Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP) +18 morewiley +1 more sourcePatient perceptions of treatment and illness when prescribed multiple medicines for co-morbid type 2 diabetes
, 2011 Illness and treatment perceptions are vital for people self-managing co-morbid conditions with associated cardiovascular disease, such as type 2 diabetes (T2D).Elliott, Rachel A; id_orcid, Rachel Elliott, null New, Stack, RJ, Gibson, J Martin, New, John P, Bundy, C, Bundy, Chris, Bundy, Christine, Rebecca Stack, null Noyce, Christine Bundy, Noyce, PR, Stack, Rebecca J, null Gibson, Gibson, JM, Elliott, Rachel A, Elliott, RA, Gibson, J Martin; id_orcid, New, JP, Noyce, Peter R +20 morecore +1 more sourceAssociations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up
Arthritis Care &Research, EarlyView.Objective
To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods
Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham +14 morewiley +1 more sourceTwo New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups [PDF]
, 2010 Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents.Marjo-Riitta Jarvelin, Martin Klingenspor, Heude, Barbara, Lévy-Marchal, C., Wichmann HE, Balkau, B, Hebebrand, J., Schürmann, A., Kiess, W., Fromme Tobias, Hartikainen, A.L., Rosskopf D, Erbel, R., Schulz N, Klingenspor Martin, Wichmann, H.-E., Schäfer H, Illig Thomas, Joeckel, Karl-Heinz, Fisher E, Johannes Hebebrand, Vogel, Carla I. G., Schulz, N, Jacques Weill, Hartikainen Anna-Liisa, Körner, A, Nöthen, MM, Krude Heiko, Borte, M, Scherag André, Froguel Philippe, Winfried Rief, Hinney A, Nöthen, M.M., Klingenspor, Martin, Hartikainen AL, Boeing Heiner, Schaefer, Helmut, Schulz, N., Rayner, Nigel W., Borte, Michael, Balkau, B., Rosskopf Dieter, Moebus, Susanne, Heinrich, Joachim, Harald Grallert, Hebebrand J, Heinrich, J., Thomas W Mühleisen, Rzehak, Peter, Klingenspor, M, Scherag S, Grallert, H., Hinney, A., Fromme, T., Vogel CI, Moebus, S, Rayner NW, Erbel, R, Dieter Rosskopf, Reinehr, T., Hartikainen, Anna-Liisa, Scherag A, Vogel, CIG, Eva Fisher, Jarvelin, Marjo-Riitta, Hartikainen, AL, Biebermann, Heike, Mühleisen TW, Vatin, V, Noethen, Markus M., Nigel W Rayner, Wichmann, H-E, Grallert H, Inga Prokopenko, Dina, C., Jarick Ivonne, Rief W, Vogel, CI, Mueller, Timo D., Prokopenko I, Berdel Dietrich, David Meyre, Berdel, D., Jarvelin, M.R., Hebebrand, Johannes, Borte Michael, Reinehr, T, Schulz Nadja, Grallert, Harald, Jarvelin, M-R, Vatin, Vincent, Joeckel, K-H, Schaefer, H, Meyre D, Jarvelin MR, Fisher Eva, Boes Tanja, Heude, B, Fisher, E, Levy-Marchal, Claire, Heiko Krude, Vogel, C.I.G., Borte M, McCarthy, MI, Koerner, Antje, Karl-Heinz Jöckel, McCarthy Mark I., Boeing H, Noethen, MM, Erbel, Raimund, Wichmann, HE, Heinrich, J, Illig T, Peter Rzehak, Jarvelin Marjo-Riitta, Mýhleisen TW, Grallert Harald, Thomas Illig, Weill, J, Levy-Marchal, C, Heude Barbara, Kovacs Peter, Jöckel, KH, Kovacs, P, Heude B, Prokopenko, Inga, Meyre, David, Rzehak Peter, Fromme, Tobias, Vogel Carla I. G., McCarthy, Mark I., Krude, H, Berdel, D, Kiess, W, Mühleisen Thomas W., Rief, W., Froguel P, Boeing, Heiner, Claire Levy-Marchal, McCarthy MI, Biebermann H, Illig, T, Mueller, TD, Christian Rimmbach, Scherag Susann, Tanja Boes, Carla I G Vogel, Vatin, V., Fisher, Eva, Heude, B., Prokopenko, I, Heike Biebermann, Reinehr Thomas, Hinney, A, Ivonne Jarick, Heiner Boeing, Christian Dina, Moebus, S., Delplanque J, Kovacs, P., Dina Christian, Fromme T, Illig, T., Weill, Jacques, Rosskopf, Dieter, Fisher, E., Reinehr, Thomas, Jöckel KH, Boes, T, Nadja Schulz, Kovacs, Peter, Moebus S, Schýrmann A, Muehleisen, TW, Heinrich Joachim, Raimund Erbel, Rosskopf, D., Prokopenko, I., Körner Antje, Scherag, Susann, Rimmbach, Christian, Dina C, Antje Körner, Koerner, A, Hebebrand, J, Scherag, S., Scherag, A, Rzehak, P., Thomas Reinehr, Rief, Winfried, Boeing, H, Reinehr T, Klingenspor M, Helmut Schäfer, Scherag, S, Schäfer, H, H-Erich Wichmann, Schäfer, H., Hebebrand Johannes, Meyre David, Rayner, N.W., Kiess, Wieland, Anke Hinney, Hinney Anke, Scherag, Andre, Meyre, D, Rosskopf, D, Hinney, Anke, Biebermann, H., Susanne Moebus, Körner A, Scherag, A., Levy-Marchal C, Müller, T.D., Delplanque, Jerome, Rief Winfried, Muehleisen, Thomas W., Müller TD, Krude, H., Rimmbach, C, Jöckel, K.-H., Rzehak P, Berdel D, Philippe Froguel, Biebermann, H, Wichmann, Heinz-Erich, Rief, W, Anna-Liisa Hartikainen, Barbara Heude, McCarthy, M.I., Jarvelin, MR, André Scherag, Jérôme Delplanque, Rayner, NW, Boes, T., Jarick I, Beverley Balkau, Rimmbach, C., Mühleisen, T.W., Mühleisen, TW, Vatin Vincent, Vincent Vatin, Hartikainen, A-L, Moebus Susanne, Schürmann, A, Delplanque, J, Michael Borte, Balkau, Beverley, Susann Scherag, Boes T, Balkau Beverley, Jarick, Ivonne, Boes, Tanja, Müller, TD, Prokopenko Inga, Borte, M., Annette Schürmann, Krude H, Berdel, Dietrich, Nöthen Markus M., Jarick, I, Müller Timo D., Schulz, Nadja, Wichmann H.-Erich, Dina, Christian, Dina, C, Mýller TD, Froguel, Philippe, Weill Jacques, Fromme, T, Rimmbach C, Grallert, H, Schuermann, Annette, Mark I McCarthy, Schäfer Helmut, Weill, J., Delplanque Jérôme, Rayner Nigel W., Kiess Wieland, Illig, Thomas, Timo D Müller, Joachim Heinrich, Balkau B, Vatin V, Tobias Fromme, Rzehak, P, Schürmann Annette, Kiess W, Körner, A., Nöthen MM, Levy-Marchal Claire, Kovacs P, Markus M Nöthen, Erbel Raimund, Wieland Kiess, Erbel R, Heinrich J, Dietrich Berdel, Klingenspor, M., Jarick, I., Schürmann A, Rimmbach Christian, Boeing, H., Froguel, P., Peter Kovacs, Krude, Heiko, Weill J, Schuermann, A, Delplanque, J., Jöckel Karl-Heinz, Biebermann Heike, Meyre, D., Froguel, P +313 morecore +1 more sourceObesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study
Arthritis Care &Research, EarlyView.Objective
Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group +7 morewiley +1 more sourceExtracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury
Advanced Healthcare Materials, EarlyView.This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney +13 morewiley +1 more source