Results 51 to 60 of about 44,340 (254)

OCDD: an obesity and co-morbid disease database

open access: yesBioData Mining, 2017
Background Obesity is a medical condition that is known for increased body mass index (BMI). It is also associated with chronic low level inflammation. Obesity disrupts the immune-metabolic homeostasis by changing the secretion of adipocytes.
Indrani Ray   +2 more
doaj   +1 more source

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya   +2 more
wiley   +1 more source

DNA methylation risk score for type 2 diabetes is associated with gestational diabetes

open access: yesCardiovascular Diabetology
Background Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown.
Teresa M. Linares-Pineda   +13 more
doaj   +1 more source

Pregnancy outcomes in type 2 versus type 1 diabetes: systematic review with meta-analyses

open access: yesEndocrine Connections
Objective: Increasing numbers of pregnancies are complicated by pregestational diabetes mellitus, especially type 2 diabetes (T2DM). Some studies have reported similar or greater risks of adverse pregnancy outcomes among women with T2DM relative to type ...
Mari Drabløs   +3 more
doaj   +1 more source

Bone mineral density and explanatory factors in children and adults with juvenile dermatomyositis at long term follow-up; a cross sectional study

open access: yesPediatric Rheumatology Online Journal, 2021
Background Juvenile dermatomyositis (JDM) is the most common idiopathic inflammatory myopathy in children and adolescents. Both the disease and its treatment with glucocorticoids may negatively impact bone formation.
Henriette Schermacher Marstein   +5 more
doaj   +1 more source

Alcohol Consumption Is a Risk Factor of Surgical Site Infection After Minimally Invasive Surgery: A Secondary Observational Analysis of a Clinical Trial

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Alcohol consumption was independently associated with Surgical Site Infection in the gastroenterological Minimally Invasive Surgery. Whether preoperative abstinence from alcohol prevents the occurrence of SSI warrants further investigation. ABSTRACT Background Surgical site infection (SSI) is one of the postoperative complications. Risk factors for SSI
Toshiya Akai   +9 more
wiley   +1 more source

Gastrointestinal morbidity in obesity [PDF]

open access: yesAnnals of the New York Academy of Sciences, 2014
Obesity is a complex disease that results from increased energy intake and decreased energy expenditure. The gastrointestinal system plays a key role in the pathogenesis of obesity and facilitates caloric imbalance. Changes in gastrointestinal hormones and the inhibition of mechanisms that curtail caloric intake result in weight gain.
Andres, Acosta, Michael, Camilleri
openaire   +2 more sources

Epidemiology of Cancer‐Associated Venous Thromboembolism Across the United States

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Prior epidemiological studies on cancer‐associated venous thromboembolism (VTE) were limited by homogenous patient populations. We leverage Cosmos, a collaborative dataset of Epic electronic health record systems, to conduct an updated evaluation of cancer‐associated VTE in the United States (US).
Barbara D. Lam   +7 more
wiley   +1 more source

The Longitudinal Effect of APOL1 Risk Alleles on Sickle Cell Anemia‐Associated Kidney Function

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Progressive kidney injury is a major cause of morbidity and mortality in sickle cell anemia (SCA). The high risk APOL1 G1/G2 variants contribute to the development of kidney disease in individuals of African ancestry, including those with SCA.
Sara R. Rashkin   +7 more
wiley   +1 more source

Evaluation of a digital FFQ using 24 h recalls as reference method, for assessment of habitual diet in women with South Asian origin in Norway

open access: yesPublic Health Nutrition
Objective: Dietary assessment tools should be designed for the target population. We developed an FFQ designed to assess diet in South Asian women in Norway.
Monica H Carlsen   +8 more
doaj   +1 more source

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