Results 181 to 190 of about 1,348,340 (308)

Assessment of occupational health hazards and associated morbidities in sanitation workers of a metropolitan city in India: a cross-sectional study

, 2023
Nilam P. Gada, Rushikesh Shukla, Pratyush Kumar, Kunal Shah, Kumar Abhishek, Manali Sarkar, Geeti Malhotra   +6 more
openalex   +2 more sources

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source

Vulvar extramammary Paget's disease with clitoral involvement: case series highlighting the role of topical treatment. [PDF]

Int J Womens Dermatol
Lopez Dominguez J, Kibbi N.
europepmc   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Ninety-Day Readmission and Morbidity Following Liver Transplantation for MASLD. [PDF]

Clin Transplant
Leslie Z, Leventhal T, Nguyen S, Leishman D, Espinoza C, Wise E, Ikramuddin S, Kandaswamy R, Matar AJ.   +8 more
europepmc   +1 more source

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

The impact of active smoking on postoperative morbidity and hernia recurrence following abdominal wall reconstruction: long-term follow-up. [PDF]

Hernia
Messer N, Horowitz A, Miller BT, Beffa LRA, Petro CC, Prabhu AS, Huang LC, Karin E, Kanani F, Nizri E, Lahat G, Szold A, Rosen MJ.   +12 more
europepmc   +1 more source

Measuring psychological morbidity for diabetes commissioning [PDF]

, 2010
Sharon Ruddock, Jackie Fosbury, A. Smith, Keith Meadows, A. Crown   +4 more
openalex   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Somatic and psychiatric aspects of complications outside the surgical area in orthognathic surgery: A retrospective study of 429 patients. [PDF]

Med Oral Patol Oral Cir Bucal
Kettunen S, Metsäranta E, Lappalainen O, Furuholm J, Snäll J.   +4 more
europepmc   +1 more source