Results 201 to 210 of about 2,354,940 (343)

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

open access: yesAdvanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie   +8 more
wiley   +1 more source

Neighborhood-level heterogeneity in childhood morbidity through generalized linear mixed models. [PDF]

open access: yesFront Public Health
Derso EA   +4 more
europepmc   +1 more source

Ubiquitination‐Dependent LLGL2 Degradation Drives Colorectal Cancer Progression via THBS3 mRNA Stabilization

open access: yesAdvanced Science, EarlyView.
During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang   +8 more
wiley   +1 more source

Global inequities in the survival of extremely preterm infants: a systematic review and meta-analysis. [PDF]

open access: yesBMC Pediatr
Getaneh T   +5 more
europepmc   +1 more source

Aligned Conductive Magnetic Nanofibers with Directional Magnetic Field Stimulation Promotes Peripheral Nerve Regeneration

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan   +4 more
wiley   +1 more source

Strengthening resilience in nursing homes: The role of emergency preparedness in mitigating COVID-19 outcomes. [PDF]

open access: yesMedicine (Baltimore)
Abahussain MA   +10 more
europepmc   +1 more source

Morbidity and health vare in Kerala: A Distributional profile and implications [PDF]

open access: yes
This paper takes up the issues pertaining to the health sector in Kerala in a larger comparative perspective in the Indian context. It would focus on the incidence of morbidity across socio-economic dimensions and their implications for economic policy ...
M.H. Suryanarayana
core  

Home - About - Disclaimer - Privacy