Results 221 to 230 of about 1,390,280 (310)

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, EarlyView.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

Profile of severe maternal morbidity cases by nationality in Colombia: analysis of national surveillance data, 2021. [PDF]

Front Glob Womens Health
Garcia Uribe JC, Arteaga Noriega A, Zuleta AM, Serna PA.   +3 more
europepmc   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Morbidity, Recurrence and Survival Following Pelvic Exenteration for Gynaecological Malignancies: A Retrospective, Single-Centre Study. [PDF]

J Clin Med
Zalawadia S, Lekka S, Al-Jumaili Z, Brockbank E, Manchanda R, Jeyarajah A, Phadnis S, Sideris M.   +7 more
europepmc   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Perioperative Determinants of Postoperative Morbidity After Liver Resection: From Morphofunctional Vulnerability to Inflammatory Response. [PDF]

J Clin Med
Pérez-Santiago L, Mora-Oliver I, Garcés-Albir M, Muñoz-Forner E, Sabater-Ortí L, Dorcaratto D.   +5 more
europepmc   +1 more source

Negative affective states and their effects on morbidity, mortality and longevity

, 2012
MD Walker, Gerald P. Duggan, N. Roulston, Amy Slack, Georgia Mason   +4 more
openalex   +2 more sources

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Validation of the Patient Health Questionnaire‐2 (PHQ‐2) in Detecting Depression Among Older Adults

AGING MEDICINE, EarlyView.
PHQ‐2 effectively screens for geriatric depression with the optimal cut‐off of 3 points. ABSTRACT Objectives Depression screening tools like the Patient Health Questionnaire‐2 (PHQ‐2) are commonly used to detect depression. However, its performance in elderly populations has been less extensively studied compared to its broader adult use.
Francesco Salis, Maristella Belfiori, Alessandro Ferrau, Eleonora Bernardini, Emanuele Concas, Anna Maria Lugas, Antonella Mandas   +6 more
wiley   +1 more source

Prevalence and risk factors of child morbidity with spatial analysis among under five children in Bangladesh. [PDF]

Sci Rep
Rashid MM, Rahman M, Miah MS, Islam MS, Roy TK, Bhuiyan MJ.   +5 more
europepmc   +1 more source