Results 101 to 110 of about 849,526 (342)

Complications of pelvic and acetabular fractures in 1331 morbidly obese patients (BMI ≥ 40): a retrospective observational study from the National Trauma Data Bank

open access: yesPatient Safety in Surgery, 2018
Background There have been no large-scale epidemiological studies of outcomes and perioperative complications in morbidly obese trauma patients who have sustained closed pelvic ring or acetabular fractures.
James T. Carson   +5 more
doaj   +1 more source

Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression [PDF]

open access: yes, 2012
Our understanding of the mechanisms by which nonalcoholic fatty liver disease (NAFLD) progresses from simple steatosis to steatohepatitis (NASH) is still very limited.
Alonso, C   +7 more
core  

Impact of Morbid Obesity on Left Ventricular Assist Device Support and Heart Transplantation [PDF]

open access: yes, 2016
Morbidly obese patients requiring LVAD support encounter higher postoperative complications and wait longer for heart transplantation, however heart transplant and graft survival is comparable.
Cohen, Sophia, Tang, Daniel, MD
core   +3 more sources

Robot-Assisted Sleeve Gastrectomy in Morbidly Obese Versus Super Obese Patients

open access: yesJSLS : Journal of the Society of Laparoendoscopic Surgeons, 2014
Background and Objectives: This study evaluates our technique for robot-assisted sleeve gastrectomy for morbidly obese and super obese patients and our outcomes.
P. Bhatia   +6 more
semanticscholar   +1 more source

Respiratory Involvement in HIST1H1E‐Related Rahman Syndrome: A Case of Severe Mixed Apnea

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Rahman syndrome (HIST1H1E‐related neurodevelopmental syndrome, OMIM #617537) is a rare autosomal‐dominant condition caused by truncating variants in the C‐terminal domain of the HIST1H1E gene. It is characterized by macrocephaly, hypotonia, craniofacial anomalies, and multisystem anomalies.
Nada Barakat   +4 more
wiley   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan   +22 more
wiley   +1 more source

Molecular Phenomics and Metagenomics of Hepatic Steatosis in Non-Diabetic Obese Women

open access: yesNature Medicine, 2018
Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal metagenomes with molecular phenomics (hepatic transcriptome and ...
L. Hoyles   +34 more
semanticscholar   +1 more source

Are There Causal Associations Between Obsessive‐Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi‐Directional Mendelian Randomization Study

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton   +217 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

Do we need to measure vitamin B12 and magnesium in morbidly obese patients with type 2 diabetes mellitus?

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2017
Anna Wåhlén,1 Arvo Haenni,2,3 Hans-Erik Johansson1–3 1Östervåla Primary Health Care Centre, Östervåla, 2Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, 3Skönvikt ...
Wåhlén A, Haenni A, Johansson HE
doaj  

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