Results 71 to 80 of about 840,804 (341)

Obesity Increases Risk‐Adjusted Morbidity, Mortality, and Cost Following Cardiac Surgery

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background Despite the epidemic rise in obesity, few studies have evaluated the effect of obesity on cost following cardiac surgery. We hypothesized that increasing body mass index (BMI) is associated with worse risk‐adjusted outcomes and higher cost ...
Ravi K. Ghanta, Damien J. LaPar, Qianzi Zhang, Vishal Devarkonda, James M. Isbell, Leora T. Yarboro, John A. Kern, Irving L. Kron, Alan M. Speir, Clifford E. Fonner, Gorav Ailawadi   +10 more
doaj   +1 more source

Dual effects of leptin in perioperative gas exchange of morbidly obese patients [PDF]

, 2018
Leptin has shown positive effects on respiratory function in experimental settings. The role of leptin on perioperative respiratory function in morbidly obese patients has not been established.
Carron, Michele, Foletto, Mirto, Gabellini, Giulia, Ieppariello, Giovanna, Martelli, Gabriele, Ori, Carlo, Perissinotto, Egle   +6 more
core   +2 more sources

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

Advanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng, Ruijie Xie, Bernd Holleczek, Hermann Brenner, Ben Schöttker   +4 more
wiley   +1 more source

Neuroanatomical Reflections of Childhood Obesity: Volumetric Analysis of the Pituitary Gland and Olfactory Bulb

Children
Introduction: Obesity is a rapidly increasing condition that leads to serious health issues. The sense of smell, one of the oldest senses related to energy metabolism, has been increasingly studied in relation to obesity.
Emel Hatun Aytaç Kaplan, Elif Bulut, Nazlı Gülsüm Akyel, Zümrüt Kocabey Sütçü, Şeyda Doğantan   +4 more
doaj   +1 more source

Multimodal Analgesia With Long-Acting Dinalbuphine Sebacate Plus Transversus Abdominis Plane Block for Perioperative Pain Management in Bariatric Surgery: A Case Report

Frontiers in Pharmacology, 2021
Laparoscopic bariatric surgery is increasingly performed in morbidly obese patients. However, post-surgical pain is common and is usually managed with classical opioids such as morphine and fentanyl.
Shih-Yuan Liu, Yi-Hong Ho, Chih-Shung Wong, Chih-Shung Wong, Chih-Shung Wong   +4 more
doaj   +1 more source

Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies [PDF]

, 2007
Peer reviewedPublisher ...
A Spinillo, AT Bianco, B Abrams, BF Abrams, CKH Yu, Doris M Campbell, GCS Smith, HA Abenheim, Institute of Medicine, J Kristensen, JA Garbaciak, JL Weiss, JM Baeten, L Rode, LC Castro, LD Odell, M Samphier, ME Cogswell, MI Cedergren, NJ Sebire, NJ Sebire, RL Naeye, S Cnattingius, SA Lederman, Siladitya Bhattacharya, Sohinee Bhattacharya, TE O'Brien, U Krishnamoorthy, UTS Kiran, W Kabiru, William A Liston   +30 more
core   +2 more sources

Trigonelline Improves Metabolism and Cardiac Function of HFpEF Mice Via Gut Microbiome Alterations‐Mediated AMPK Activation

Advanced Science, EarlyView.
Metabolomics analyses reveal that trigonelline is markedly reduced in HFpEF hearts. Trigonelline supplementation alleviates metabolic disorders and improves cardiac function in HFpEF mice via gut microbiota‐mediated AMPK activation. Abstract Heart failure with preserved ejection fraction (HFpEF) is a prevalent end‐manifestation of cardiovascular ...
Zhe Cheng, Xiaowen Wang, Jiang Yu, Xiaorong Li, Qing Tang, Can Qu, Ding Yang, Yuanjing Li, Yong Xia, Yongzheng Guo   +9 more
wiley   +1 more source

Association of miR-34a and miR-143 levels with PPARγ gene expression in adipose tissues of non-diabetic adults

Journal of Physiological Anthropology, 2022
Background Peroxisome proliferator-activated receptor gamma (PPARγ) is a promising therapeutic molecule. Epigenetic mechanisms, including non-coding RNAs, regulate the expression level of the PPARγ gene. Objective We aimed to examine the PPARγ expression
Maryam Zarkesh, Kimia Tabaei, Mahdi Akbarzadeh, Afsoon Daneshafrooz, Azita Zadeh-Vakili   +4 more
doaj   +1 more source

Double Burden of Malnutrition Among Undergraduates in Ogun State Nigeria [PDF]

, 2015
Coexistence of under and over nutrition among the same population group is referred to as the double burden of malnutrition. The objective of this study was to assess double burden of malnutrition among undergraduate students in Ogun State Nigeria.
Ekerette, N. N. (Nkereuwem), Oladoyinbo, C. A. (Catherine)   +1 more
core   +2 more sources

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source