Results 131 to 140 of about 6,612,409 (279)

Interspecies coexistence and environmental sensitivity in urban design: a qualitative study in Onex, Switzerland

[i2]: Investigación e Innovación en Arquitectura y Territorio
A qualitative analysis was conducted of data collected from the project L'étendue sauvage. remarquer le monde qui nous échappe, conducted in Onex, Switzerland, in the summer of 2022.
Aitor Frías-Sánchez, Estefanía Mompean Botias   +1 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Climate adaptation in urban space: the need for a transdisciplinary approach

Frontiers in Sustainable Cities
Climate change demands innovative and holistic approaches to urban design that address both the tangible and intangible challenges posed by a rapidly evolving environment.
Sara Lenzi, Sara Lenzi, Juan Sádaba, Aiur Retegi   +3 more
doaj   +1 more source

Emergency egress requirements for Space Station Freedom [PDF]

There is a real concern regarding the requirements for safe emergency egress from the Space Station Freedom (SSF). The possible causes of emergency are depressurization due to breach of the station hull by space debris, meteoroids, seal failure, or vent ...
Ray, Paul S.
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Research-Creation and More-Than-Human Collaboration

Imaginations: Journal of Cross-Cultural Media Studies
This is a set of guiding principles for more-than-human collaboration in research-creation. As slippery terms with unclear boundaries, we must form practical and theoretical protocols to navigate multispecies activities that benefit the emerging ...
Oriana Confente
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Governance in the gullies : democratic responsiveness and leadership in Delhi's slums [PDF]

The authors use detailed ethnographic evidence to design and interpret a broad representative survey of 800 households in Delhi's slums, examining the processes by which residents gain access to formal government and develop their own informal modes of ...
Jha, Saumitra, Rao, Vijayendra, Woolcock, Michael   +2 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Articulating Felt Senses for More-Than-Human Design: A Viewpoint for Noticing

Designing Interactive Systems Conference
To rigorously approach the more-than-human world in design research, we need to become more receptive and better equipped to describe the complexities of relationality. In response, this paper advocates for the articulation of the felt sense -or tacit knowledge residing in our bodies- as a viewpoint for noticing.
Claudia Núñez-Pacheco, Anton Poikolainen Rosén   +1 more
openaire   +4 more sources