Results 131 to 140 of about 6,659,298 (299)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Open PhilosophyIn response to this issue’s theme of Can robots be sensual? two propositions are discussed from a design researcher’s perspective. Four devices across two speculative projects Habitat Robots and Soil Protector Robots are presented.
Santer Steven C.
doaj +1 more source
Strategically using public housing assets could transform our middle suburbs [PDF]
‘Greyfields’ in the Australian context have been defined as those ageing but occupied tracts of inner and middle ring suburbia that are physically, technologically and environmentally failing.
Shane Murray +9 more
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Decent Work and Women's Economic Empowerment: Good Policy and Practice [PDF]
, 2012 Women constitute half of humankind and 40% of the global workforce. They are a growing proportion of the overseas migrant labour force. As workers, entrepreneurs and service providers they contribute actively to social and economic development.Yet women ...
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Summary of a Crew-Centered Flight Deck Design Philosophy for High-Speed Civil Transport (HSCT) Aircraft [PDF]
Past flight deck design practices used within the U.S. commercial transport aircraft industry have been highly successful in producing safe and efficient aircraft.
Abbott, Terence S. +4 more
core +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Friction in Games and Computational Media (Editorial)
Journal of Digital Media & InteractionThe issue is organised into four groups: Play; Art; Human; More-than-Human. The articles in the first group, Play, aim at exploring roles and expressions of friction within play and games. In Exploring Friction in Refugee Narratives: The Cases of Bury Me,
Miguel Carvalhais, Pedro Cardoso
doaj +1 more source