Results 81 to 90 of about 6,612,409 (279)

Designing the Urban Coexistence

Anales de Investigación en Arquitectura
This paper critically examines the prevailing paradigms of environmental and spatial justice, emphasising the existing disparities in policies that predominantly favour human interests while overlooking the fundamental rights and well-being of non-human
Filippo Vegezzi
doaj   +3 more sources

Wide-Scale Analysis of Human Functional Transcription Factor Binding Reveals a Strong Bias towards the Transcription Start Site [PDF]

, 2007
We introduce a novel method to screen the promoters of a set of genes with shared biological function, against a precompiled library of motifs, and find those motifs which are statistically over-represented in the gene set.
A Ambesi-Impiombato, A Blais, A Eto, A Subramanian, AE Kel, AG Clark, AL Lam, AM McGuire, Anat Reiner, Assif Yitzhaky, B Ren, C Kimura-Yoshida, C Plessy, C Yang, CT Harbison, D Pfeifer, D Wang, DB Allison, E Emberly, E Segal, Eytan Domany, FP Roth, GC Pipes, GC Yuan, GQ Yao, GZ Hertz, H Li, H Lodish, J Zheng, JD Hughes, JL DeRisi, JQ Ling, K Frech, K Quandt, KD MacIsaac, L Amir-Zilberstein, L Elnitski, L Marino-Ramirez, L McCue, M Ashburner, M Kellis, M Milyavsky, MA Nobrega, Mark Koudritsky, MC Frith, ML Howard, ML Whitfield, N Rajewsky, Or Zuk, P Carninci, P Carninci, P Cliften, PM Haverty, PR Buckland, R Elkon, R Liu, R Sharan, Ran Brosh, S Aerts, S Rashi-Elkeles, S Tavazoie, SJ Cooper, SJ Ho Sui, Sui Huang, U Gerland, Varda Rotter, WW Wasserman, X Xie, Y Barash, Y Benjamini, Y Benjamini, Y Tabach, Yossi Buganim, Yuval Tabach, Z Wang   +74 more
core   +5 more sources

Introducing More-Than-Human Design in Practice

Interactions
In this forum, we explore more-than-human design practices that consider the interactions and interdependencies between humans and nonhuman others, including animals, plants, water, bacteria, sensors, and data. --- Anton Poikolainen Rosén and Sara Heitlinger, Editors
Poikolainen Rosén, A., Heitlinger, S.
openaire   +2 more sources

The making(s) of more-than-human design: introduction to the special issue on more-than-human design and HCI

Human–Computer Interaction
Human activities have drastically altered the planet, with design playing a significant role. While design may intend to do good, its consequences are not always positive: from climate change to resource depletion to unforeseen social dynamics. These transformations also include ourselves, as our relationships with new technologies blur and complicate ...
Elisa Giaccardi, Johan Redström, Iohanna Nicenboim   +2 more
openaire   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Building Liveable Futures: Dwelling as Collaborative Survival After Climate Change

Text Matters
Taking a cue from Tim Ingold’s post-humanist reflection on building and dwelling as more-than-human practices, the article aims to revisit dwelling as a strategy of “collaborative survival” (Tsing) in the context of the ongoing climate emergency. Drawing
Mateusz Chaberski
doaj   +1 more source

Design for the Right to the Smart City in More-than-Human Worlds [PDF]

Environmental concerns have driven an interest in sustainable smart cities, through the monitoring and optimisation of networked infrastructure processes.
Comber, R., Heitlinger, S.
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Product-Related Risk and Cognitive Biases: The Shortcomings of Enterprise Liability [PDF]

, 2000
Products liability law has witnessed a long debate over whether manufacturers should be held strictly liable for the injuries that products cause. Recently, some have argued that psychological research on human judgment supports adopting a regime of ...
Henderson, James A., Jr., Rachlinski, Jeffrey J.   +1 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source