ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
British Journal of Pharmacology, EarlyView.G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison +15 more
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Analgesic effects of intrathecal bupivacaine with neostigmine or morphine among elective surgical patients in selected comprehensive specialised hospitals, Southern Ethiopia: a prospective cohort study. [PDF]
BMJ OpenDelmolo NS +11 more
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Progress on the development of Class A GPCR‐biased ligands
British Journal of Pharmacology, EarlyView.Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
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THE SEPARATION AND ESTIMATION OF MORPHINE, PSEUDOMORPHINE, AND RELATED SUBSTANCES
, 1927 A.K. Balls
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Report of the Committee Appointed by the Section of Obstetrics and Gynæcology to Investigate the Effects of Scopolamine-Morphine Narcosis, “Twilight Sleep,” in Childbirth [PDF]
, 1918 openalex +1 more source
Optimizing Intrathecal Opioid Strategies for Cesarean Section: A Comprehensive Narrative Review of Pharmacology, Clinical Outcomes, and Safety. [PDF]
CureusMoisa RC +6 more
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Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
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The Potential Use of Cannabidiol in the Treatment of Opioid Use Disorder: A Systematic Review. [PDF]
Addict BiolShafie M +9 more
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British Journal of Pharmacology, Volume 182, Issue 11, Page 2354-2373, June 2025.Sex differences in the effects of maternal voluntary editable Cannabis consumption on the metabolic phenotype of adult offspring on a high‐fat diet. Abstract Background and Purpose Given the recent rise in Cannabis legalisation, accessibility to Cannabis and consumption have increased during pregnancy. Therefore, there could be unintended developmental
Nada A. Sallam +5 more
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