Results 271 to 280 of about 270,592 (355)

Network pharmacology approach to unveiling the mechanism of berberine in the amelioration of morphine tolerance. [PDF]

open access: yesJ Tradit Chin Med
Shuai H   +6 more
europepmc   +1 more source

Dopamine D3 receptor blockade accelerates the extinction of opioid withdrawal‐induced drug‐seeking behaviours and alters microglia in dopaminoceptive nuclei

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Among all drugs of abuse, opioids cause most of the deaths and treatment seeking. Despite abundant research in multifaceted therapeutic strategies, a high rate of relapse still characterises this condition. Dopamine D3 receptor antagonists combined with cue‐exposure therapies have been proposed to ameliorate the abused drugs ...
Aurelio Franco‐García   +3 more
wiley   +1 more source

Opioid receptors in cardiovascular function

open access: yesBritish Journal of Pharmacology, EarlyView.
Opioid receptors are G protein‐coupled receptors expressed by various cells in the heart, including myocytes and nerve fibres, and play a crucial role in modulating cardiac function. These receptors influence neural transmission, heart rate and myocyte contractility, offering cardioprotection.
Venkatesh Katari   +4 more
wiley   +1 more source

A Scoping Review of the Emergence of Novel Synthetic Opioids in Australian Drug Markets: What Does This Mean for Harm Reduction Responses?

open access: yesDrug and Alcohol Review, EarlyView.
ABSTRACT Issues Rising synthetic opioid deaths in North America, and the emergence of nitazene harms has driven concern about novel synthetic opioids (NSO) in Australia. This scoping review aimed to map what is known about NSOs in Australia. Approach Scoping review of peer‐reviewed and grey literature on NSO detections and harms.
Emmanuel Mammoliti   +2 more
wiley   +1 more source

Changes in cortical delta power during chronic invasive epilepsy monitoring

open access: yesEpilepsia, EarlyView.
Abstract Objective Cortical delta band (1–4 Hz) activity is considered a biomarker for states of altered consciousness, with increased delta power observed during anesthesia, sleep, coma, and delirium. The current study sought to characterize delta power following electrode implantation with respect to patient demographics and clinical characteristics ...
Emily R. Dappen   +4 more
wiley   +1 more source

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