Network pharmacology approach to unveiling the mechanism of berberine in the amelioration of morphine tolerance. [PDF]
Shuai H+6 more
europepmc +1 more source
Cordycepin ameliorates morphine tolerance by inhibiting spinal cord ferroptosis and inflammation via targeting SIRT1. [PDF]
Li Z+8 more
europepmc +1 more source
Background and Purpose Among all drugs of abuse, opioids cause most of the deaths and treatment seeking. Despite abundant research in multifaceted therapeutic strategies, a high rate of relapse still characterises this condition. Dopamine D3 receptor antagonists combined with cue‐exposure therapies have been proposed to ameliorate the abused drugs ...
Aurelio Franco‐García+3 more
wiley +1 more source
Transcutaneous Auricular Vagus Nerve Stimulation Restores Cognitive Impairment in Morphine-Withdrawn Rats: Role of BDNF and Glial Cells in the Hippocampus. [PDF]
Nazari S+6 more
europepmc +1 more source
Opioid receptors in cardiovascular function
Opioid receptors are G protein‐coupled receptors expressed by various cells in the heart, including myocytes and nerve fibres, and play a crucial role in modulating cardiac function. These receptors influence neural transmission, heart rate and myocyte contractility, offering cardioprotection.
Venkatesh Katari+4 more
wiley +1 more source
Tolerability of different doses of oliceridine versus traditional opioids in acute pain management: a systematic review and meta-analysis. [PDF]
Liu Y, Zhu Y, Fu H.
europepmc +1 more source
ABSTRACT Issues Rising synthetic opioid deaths in North America, and the emergence of nitazene harms has driven concern about novel synthetic opioids (NSO) in Australia. This scoping review aimed to map what is known about NSOs in Australia. Approach Scoping review of peer‐reviewed and grey literature on NSO detections and harms.
Emmanuel Mammoliti+2 more
wiley +1 more source
Research progress on the impact of opioids on the tumor immune microenvironment (Review). [PDF]
Zhou Y, Li W, Chen Y, Hu X, Miao C.
europepmc +1 more source
Changes in cortical delta power during chronic invasive epilepsy monitoring
Abstract Objective Cortical delta band (1–4 Hz) activity is considered a biomarker for states of altered consciousness, with increased delta power observed during anesthesia, sleep, coma, and delirium. The current study sought to characterize delta power following electrode implantation with respect to patient demographics and clinical characteristics ...
Emily R. Dappen+4 more
wiley +1 more source