Results 311 to 320 of about 397,909 (400)

The Risk Factors and Mortality Among Patients With Different Combination Patterns of Opioids and Benzodiazepines: A Retrospective Study

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT The concurrent use of opioids and benzodiazepines (BZDs) has raised safety concerns due to increased risks of respiratory depression and death. To evaluate mortality risks linked to different patterns of co‐prescription, we conducted a retrospective cohort study using data from a private hospital system between 2008 and 2018.
Fang‐Yu Su   +3 more
wiley   +1 more source

Managing Drug–Drug Interactions Involving the Non‐Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Loperamide is a widely used nonprescription peripherally acting opioid indicated for diarrhea. Loperamide undergoes extensive first‐pass metabolism, primarily by cytochrome (CYP) 3A and CYP2C8, with minor contributions from CYP2B6 and CYP2D6, and intestinal efflux by P‐glycoprotein (P‐gp).
Zhu Zhou   +6 more
wiley   +1 more source

Airway management and mechanical ventilation using the Ventrain in a cat for surgical repair of an intrathoracic tracheal avulsion

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract This report describes the complex management of an 11‐month‐old male cat with an intrathoracic tracheal avulsion following blunt trauma, a rare but critical injury typically associated with vehicular accidents. Presenting with severe dyspnoea 10 days after a car accident, the cat exhibited a marked narrowing of the tracheal lumen to 1.2 mm ...
Johanna Vuille‐dit‐Bille   +2 more
wiley   +1 more source

Pathological fracture secondary to an aneurysmal bone cyst in the proximal femur of a 5‐year‐old French bulldog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 5‐year‐old, male, neutered French bulldog was referred with a 24‐hour history of left hindlimb lameness. The patient presented with a 9/10 grade left pelvic limb lameness and pain on full extension of the left hip joint. Radiographs, computed tomography and ultrasound‐guided fine needle aspirates were performed, leading to a presumptive ...
Carolyn Averil Hylton   +4 more
wiley   +1 more source

Effective management of chronic lumbar back pain in five dogs using an erector spinae plane block

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract This retrospective case series evaluates the use of the ultrasound‐guided erector spinae plane block for managing chronic lumbar pain in five dogs unresponsive to conventional systemic analgesia. Each patient received a bilateral erector spinae plane block at either the L2/L3 or L3/L4 level under general anaesthesia. The injectate consisted of
Nathalie Haslinger, Katrin Ertelt
wiley   +1 more source

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