Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach
Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya +7 more
wiley +1 more source
Analysis of <i>OTX2</i>, <i>PAX6</i>, and <i>SOX2</i> Gene and Protein Expression Patterns in Ocular Development of Human and Rat Embryos. [PDF]
Junga A, Pilmane M, Fedirko P.
europepmc +1 more source
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
J. Huelsken +4 more
semanticscholar +1 more source
Grooved Surface of the Obturator Internus Muscle With Two Distinct Adjacent Parts
ABSTRACT The specific anatomical features of the obturator internus, particularly those of its medial surface, remain insufficiently characterized. This study investigated the morphology of the obturator internus muscle by focusing on the shape of its medial surface and potential age‐related changes.
Satoru Muro +4 more
wiley +1 more source
From Genes to Malformations: Molecular Mechanisms Driving the Pathogenesis of Congenital Anomalies of the Kidney and Urinary Tract. [PDF]
Fourikou M, Dotis J.
europepmc +1 more source
The extracellular matrix in development and morphogenesis: a dynamic view.
Tania Rozario, D. DeSimone
semanticscholar +1 more source
Interaction Between Actin and Microtubules During Plant Development
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu +3 more
wiley +1 more source
Auxin Biosynthesis, Transport, Signaling, and Its Roles in Plant Leaf Morphogenesis. [PDF]
Zheng H +6 more
europepmc +1 more source
Making Two out of One: Kinesin Motors Driving Plant Cell Division
ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley +1 more source

