Results 181 to 190 of about 6,133,036 (272)

Hac1-independent functions of Ire1 drive morphogenesis in Candida albicans through distinct transcriptional programs. [PDF]

J Cell Sci
Stack-Couture S, Nunes Marsiglio Librais G, Lung B, Genereaux J, Halder V, Dumeaux V, Shapiro RS, Lajoie P.   +7 more
europepmc   +1 more source

The International Consortium for Arthrogryposis: A Collaborative Framework for Early Detection, Care, Research, and Education

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is a group of rare congenital conditions, characterized by multiple joint contractures but may involve any body system including central nervous system. AMC is etiologically heterogeneous, with over 400 genetic and many non‐genetic causes implicated in its prenatal development.
Shahrzad Nematollahi, Noa Bouzaglo, Victoria Castillo Sanchez, Johanna I. P. de‐Vries, Klaus Dieterich, Alicja Fafara, Isabel Filges, Philip Giampietro, Göknur Haliloğlu, Judith Hall, Coleman Hilton, Remco Jansen, Valentina Maestri, Carolina Navalon, Daniel Natera de Benito, Tony Pan, Ani Samargian, Bonita Sawatzky, Harold van Bosse, Paul A. Trainor, Noémi Dahan‐Oliel   +20 more
wiley   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Dynamics, function, and regulation of mammary stem cells in development and disease. [PDF]

Exp Mol Med
Lee E, Tao Y, Wang AJ, Kang Y.
europepmc   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

Construction and application of mammary and breast cancer organoids. [PDF]

Cell Insight
Meng Y, Bai P, Zhang L, Zhang M, Cai C.
europepmc   +1 more source

Biomimetic Nanofiber Scaffold Coated With Acellular Matrices for Uterine Myometrial Tissue Engineering

Advanced NanoBiomed Research, EarlyView.
Schematic representation of acellular matrix generation from human uterine fibroblast cells, coating on polycaprolactone electrospun nanofibers, and subsequent in vitro and in vivo characterization. A tissue‐engineered scaffold tailored for uterine myometrium‐specific regeneration is designed. The electrospinning technique was used to fabricate aligned
Srividya Hanuman, Shripad S. Hebbar, Rishikesh Balvalli, Manasa Nune   +3 more
wiley   +1 more source

A spatiotemporal single-cell transcriptomic atlas reveals fertilization-induced auxin signaling driving strawberry fruit set and development. [PDF]

Nat Commun
Ma Z, Zhang M, Tian G, Li W, Zhang Y, Liang X, Gao S, Zhao X, Zhu C, Guo Y, Kang C, Lian H, Xu P, Yu J, Liu T, Xiao W, Li L, Liu Z, Han X, Zhou J.   +19 more
europepmc   +1 more source

Glycolytic suppression of cell adhesion promotes thyroid morphogenesis in response to nutrition. [PDF]

EMBO Rep
Shindo A, Nishiguchi S, Fujiwara A, Nakashima K.   +3 more
europepmc   +1 more source

Mechanotransduction and cell fate: from molecular sensors to multicellular self-organization. [PDF]

Front Cell Dev Biol
Estrada Elorza MDC, Cruz-Lemini M, Martínez-Mayorga K, Martinez-Garfias MG, Gómez-Carrillo AC, Rios-Perez A, Granados-Montiel J.   +6 more
europepmc   +1 more source