Results 101 to 110 of about 18,579 (227)

Organocatalytic Formal (3+2+1)‐Cycloaddition of Allenoates, Michael Acceptors, and Carbaldehydes

open access: yesChemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.
The use of secondary amine Lewis base organocatalysts allows for the unprecedented activation of allenoates for formal (3+2+1)‐cycloadditions with Michael acceptors and aromatic carbaldehydes. ABSTRACT Employing secondary amines as covalently interacting Lewis basic organocatalysts allows for the activation of electron‐deficient allenes (allenoates ...
David Naderer   +5 more
wiley   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

open access: yesAngewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Peptide Thioester and Triazole Derivatives Through On‐Resin Dual‐Modification of Peptide Thiosulfonates

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 38, 14 September 2026.
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner   +5 more
wiley   +1 more source

Remapping the Synthetic Landscape of α‐Tertiary Alkylamines via Dual‐Functional Catechol

open access: yesAngewandte Chemie, Volume 138, Issue 37, 7 September 2026.
A three‐component assembly strategy has been developed for the modular synthesis of hindered α‐tertiary aliphatic amines from readily available precursors through unlocking the dual role of catechol. The practicality of this methodology has been demonstrated in over 90 examples, including compounds that are otherwise difficult to access, along with ...
Chen‐Yan Cai, Yuzuru Kanda, Tian Qin
wiley   +2 more sources

A New Sustainable Approach to Antibiotic Resistance: Development of bis‐Quaternary Ammonium Salts From 2,4,6‐Trichloro‐1,3,5‐Triazine

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
Antibiotics improved human life, but bacterial resistance makes surfaces and packaging disinfection critical. Quaternary ammonium salts (QAS) represent a possible alternative. In this work, new bis‐cationic QAS from 2,4,6‐trichloro‐1,3,5‐triazine (bis‐TQAS) were synthesized, showing excellent inhibition against Klebsiella pneumoniae, Escherichia coli ...
Rachele Rampazzo   +5 more
wiley   +1 more source

MORPHOLINE [PDF]

open access: yesChemical & Engineering News Archive, 1953
openaire   +1 more source

Piperazine and Morpholine Protoporphyrin IX Derivatives Intensify Biomolecules Oxidation and Phototoxicity in Triple‐Negative Breast Cancer

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
Protoporphyrin IX derivatives bearing piperazine or morpholine substituents exhibit enhanced cellular retention and photodynamic activity in triple‐negative breast cancer cells. Structural modification promotes oxidative stress, alters mitochondrial membrane potential, and increases caspase‐3 activity, providing new structure–activity relationship ...
Maynne Duarte Suriani Franco   +11 more
wiley   +1 more source

A Solvent‐Free Approach for the Mechanochemical Upcycling of Bio‐ and Fossil‐Based Polyesters Into Value‐Added Chemicals and Bio‐Based Plasticizers

open access: yesChemSusChem, Volume 19, Issue 17, 14 September 2026.
Mechanochemical upcycling of bio‐ and fossil‐based polyesters with alcohols and amines using MeONa as the catalyst selectively produces synthetically useful diesters and diamides, giving only alcohols as byproducts. This green and efficient protocol is readily scalable and can be transferred to the upcycling of polyester‐based postconsumer waste ...
Divya Jain   +5 more
wiley   +1 more source

Modular assembly and property profiling of an expansive, shape-defined library of pentacyclic saturated N-heterocycles. [PDF]

open access: yesChem Sci
Boschi E   +12 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy