Results 61 to 70 of about 5,145,073 (302)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Humicola ovoideum sp. nov. and Pseudohumicola obscura sp. nov., Two Novel Chaetomiaceae Species Reported in Korea

open access: yesMycobiology
During an investigation of soil micro-fungi in Korea, two fungal strains designated as strains KNU-1816T and KNUF-20-124T were isolated from soil samples collected from Gyeongbuk province.
Hae-Dam Kim   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Identification and Characterization of Five Previously Unrecorded Penicillium Species of Subgenus Aspergilloides Isolated in Korea

open access: yesMycobiology
In a survey of freshwater and near-freshwater soils in Chungbuk, Gyeonggi, Gangwon, Gyeongbuk, and Gyeongnam provinces in Korea, seven fungal strains were isolated and identified as members of the genus Penicillium based on the internal transcribed ...
Min-Gyu Kim   +7 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Measuring Morphological Productivity [PDF]

open access: yes, 2010
Pustylnikov O, Schneider-Wiejowski K. Measuring Morphological Productivity. Studies in Quantitative Linguistics.
Schneider-Wiejowski, Karina   +1 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Discovery of two new Cortinarius species in Southern China

open access: yesFrontiers in Microbiology
IntroductionCortinarius are globally distributed mushrooms, all of whom form mycorrhizae, and are characterized by rust-brown to brownish-red spores. The high species richness of the genus results in significant morphological diversity overall, alongside
Yuxiao Dang   +18 more
doaj   +1 more source

Morphological and molecular genetic diversity analyses in Helianthus annuus (L.)

open access: yesElectronic Journal of Plant Breeding, 2016
The knowledge of genetic diversity among parental lines is a prerequisite for selecting parents for hybridization in any heterosis breeding programme. Evaluation of 13 parental lines using D2 analysis was undertaken during spring 2014 at PAU, Ludhiana ...
Mohd Shamshad and, S.K. Dhillon
doaj   +1 more source

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