Results 141 to 150 of about 1,217,314 (291)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

UNELE ASPECTE TAXONOMICE ALE STUDIERII GENULUI ANABAENOPSIS

Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2017
În prezentul articol se face o sistematizare a rezultatelor prezentate în literatura de specialitate din domeniu. Aborda­rea genului Anabaenopsis începe cu istoricul investigaţiei lui, fiind relevate modificările sistematice, evidenţiat numărul de specii
Galina DOBROJAN
doaj  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Comparison of five Calligonum species in Tarim Basin based on morphological and molecular data [PDF]

, 2013
Five Calligonum species endemic to the Tarim Basin – C. roborowskii, C. kuerlese, C. juoqiangense, C. yengisaricum, and C. taklimakanense – were compared using 14 morphological characteristics and nrDNA ITS and cpDNA trnL-F molecular data.
Abdurahman, Maryamgul, Liu, Bin, Pan, Borong, Sabirhazi, Gulnur, Yin, Linke   +4 more
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Comparative growth and management of white and red clovers [PDF]

, 2009
peer-reviewedThe aim of this paper is to provide the underpinning scientific basis for the optimum management of white and red clovers. Critical morphological and canopy characteristics which influence the yield and persistence of white and red clover in
Black, Alistair D, Laidlaw, A.S., Moot, D.J., O'Kiely, Padraig   +3 more
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

A simple morphodynamic model for sand banks and large-scale sand pits subject to asymetrical tides [PDF]

, 2001
We extend existing knowledge on theoretical growth characteristics of tidal sand banks by including asymmetrical tides with an M0, M2 and M4-constituent, thus allowing for migration.
Hulscher, Suzanne J.M.H., Ikeda, S., Nemeth, Attila, Peters, B.G.T.M., Roos, Pieter C.   +4 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source