Results 81 to 90 of about 6,466,944 (302)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

VIABILITY CHARACTERISTICS AND PHYSIOLOGICAL BEHAVIORS IN CABBAGE SEEDS IN DEPENDS ON STAGE OF MATURITY [PDF]

open access: yesJournal of Central European Agriculture, 2009
The main purposes of the present study were to establish the changes during different stage of maturity and development of cabbage seed as well as earliest behaviors of viability and harvesting data.
Nikolay Panayotov, Nevena STOEVA
doaj  

The effect of irrigation with wastewater fish ponds on the quality of peanut, (Arahis hypogeae)

open access: yesالمجلة العراقية للاستزراع المائي, 2019
The research was carried out at Alsen research center of the General Authority for Fisheries in the Banias region–Tartus Governorate - during two agricultural seasons 2018-2019, in order to study the effect of irrigation with fish culture effluent on ...
Ali S. Othman   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Some morphological characteristics of turkish shepherd dogs raised in breeder conditions various countries [PDF]

open access: yesEurasian Journal of Veterinary Sciences
Aim: This research was conducted to compare some morphological characteristics of shepherd dogs, phenotypically similar to Turkish shepherd dogs, raised in public areas in Turkey, Iran, Azerbaijan and Uzbekistan.
Cafer Tepeli   +4 more
doaj  

A theoretical insight into morphological operations in surface measurement by introducing the slope transform [PDF]

open access: yes, 2015
As one of the tools for surface analysis, morphological operations, although not as popular as linear convolution operations (e.g. the Gaussian filter), are really useful in mechanical surface reconstruction, surface filtration, functional simulation etc.
Lou, Shan   +6 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Habitat-specific morphological variation among threespine sticklebacks (Gasterosteus aculeatus) within a drainage basin [PDF]

open access: yes, 2011
MMW was funded by a Natural Environment Research Council studentship (NERC, UK) awarded to PJBH. AJWW was supported by a DVC Grant from the University of Sydney.Habitat-specific morphological variation, often corresponding to resource specialization, is ...
Hart, Paul J. B.   +18 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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