Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Effect of Morphological Characteristics and Motor Abilities on the Execution of Technical Elements in Alpine Skiing [PDF]
Testing was conducted on a sample of 35 subjects, students of the Faculty of Sport and Physical Education in Niksic, who attend regular classes of the Based skiing.
Marija Bubanja +2 more
doaj
The effect of irrigation with wastewater fish ponds on the quality of peanut, (Arahis hypogeae)
The research was carried out at Alsen research center of the General Authority for Fisheries in the Banias region–Tartus Governorate - during two agricultural seasons 2018-2019, in order to study the effect of irrigation with fish culture effluent on ...
Ali S. Othman +3 more
doaj +1 more source
Predicting the morphological characteristics and basic density of Eucalyptus wood using the NIRS technique [PDF]
This research aimed to apply the near infrared spectroscopy technique (NIRS) for fast prediction of basic density and morphological characteristics of wood fibers in Eucalyptus clones.
Gherardi Hein, Paulo Ricardo +4 more
core
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Some morphological characteristics of turkish shepherd dogs raised in breeder conditions various countries [PDF]
Aim: This research was conducted to compare some morphological characteristics of shepherd dogs, phenotypically similar to Turkish shepherd dogs, raised in public areas in Turkey, Iran, Azerbaijan and Uzbekistan.
Cafer Tepeli +4 more
doaj
RELATIONS BETWEEN THE MORPHOLOGICAL CHARACTERISTICS OF GRAMMAR SCHOOL FEMALE STUDENTS AND THE RESULTS ACHIEVED AT PRACTISING ON THE BEAM [PDF]
This research was done on a sample of 104 grammar school female students, aged between 12 and 14, in order to discover the influence of the morphological characteristics on the result efficiency at practising on the beam.
Miladin Jovanović +2 more
doaj
The Nature of Composite LINER/HII Galaxies, As Revealed from High-Resolution VLA Observations [PDF]
A sample of 37 nearby galaxies displaying composite LINER/HII and pure HII spectra was observed with the VLA in an investigation of the nature of their weak radio emission.
Clark B. G. +37 more
core +2 more sources

