Results 51 to 60 of about 349,685 (286)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hyperspectral colon tissue cell classification [PDF]

open access: yes, 2004
A novel algorithm to discriminate between normal and malignant tissue cells of the human colon is presented. The microscopic level images of human colon tissue cells were acquired using hyperspectral imaging technology at contiguous wavelength intervals ...
Rajpoot, Kashif   +2 more
core  

Characterizing neuromorphologic alterations with additive shape functionals

open access: yes, 2004
The complexity of a neuronal cell shape is known to be related to its function. Specifically, among other indicators, a decreased complexity in the dendritic trees of cortical pyramidal neurons has been associated with mental retardation.
Barbosa, M. S.   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Phylogenetic analysis of stemmed points from Patagonia: Shape change and morphospace evolution

open access: yesJournal of Lithic Studies, 2018
This work is focused in the study of Patagonian lithic projectile points shape variation from a phylogenetic perspective pursuing three main aims: first, generate a model of projectile point shape diversification and morphospace evolution; second ...
Marcelo Cardillo, Judith Charlin
doaj   +1 more source

Urban dynamics in the Flemish countryside: a comparative study on morphological patterns and local economy dynamics [PDF]

open access: yes, 2011
The article examines two aspects of urbanisation in the rural areas of Flanders, the northern part of Belgium. On the one hand, the evolution of the built environment is studied in terms of built-up density and the corresponding morphological sprawl ...
Allaert, Georges   +3 more
core   +1 more source

Stellar and Molecular Gas Kinematics of NGC1097: Inflow Driven by a Nuclear Spiral

open access: yes, 2009
We present spatially resolved distributions and kinematics of the stars and molecular gas in the central 320pc of NGC1097. The stellar continuum confirms the previously reported 3-arm spiral pattern extending into the central 100pc.
Davies, R.   +5 more
core   +1 more source

Detection of dirt impairments from archived film sequences : survey and evaluations [PDF]

open access: yes, 2010
Film dirt is the most commonly encountered artifact in archive restoration applications. Since dirt usually appears as a temporally impulsive event, motion-compensated interframe processing is widely applied for its detection. However, motion-compensated
Ren, Jinchang, Vlachos, T.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Construction and Optimization of an Ecological Network in Funiu Mountain Area Based on MSPA and MCR Models, China

open access: yesLand, 2023
Rapid urbanization has led to a significant expansion of urban space, causing ecological problems such as fragmentation, declining landscape connectivity, and decreasing biodiversity.
Zechen Wang   +5 more
doaj   +1 more source

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