Results 121 to 130 of about 1,633,995 (265)

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

Looks Can Be Deceiving: Morphological Traits Are Weakly Associated With the Isotopic Niches of Freshwater Fishes [PDF]

Aim Fueled by the emergence of global-scale databases, fish morphological traits are now routinely used as a proxy for trophic ecology when estimating functional diversity.
Boulêtreau, S., Keppeler, F.W., Jardine, T.D., Perga, M., Cucherousset, J., Olden, J.D., Harrod, C., Tedesco, P., Vagnon, C., South, J., Jackson, M.C., McIntosh, A.R., Jackson, MC, Cucherousset, Julien, Jardine, Timothy D., McIntosh, Angus R., South, J, South, Josie, Harrod, C, Keppeler, Friedrich W., Perga, ME, Cucherousset, J, Jackson, Michelle C., McIntosh, AR, Olden, JD, Keppeler, FW, Boulêtreau, S, Perga, Marie‐Elodie, Vagnon, Chloé, Tedesco, Pablo, Tedesco, P, Vagnon, C, Harrod, Chris, Olden, Julian D., Boulêtreau, Stéphanie, Jardine, TD   +35 more
core   +1 more source

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

Advanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree, Jinwoo Sung, Yutaro Miki, Ryuju Suzuki, Yoshitaka Koseki, Kunikazu Ishii, Minsang Kim, Keita Tanita, Kota Sato, Toru Nakazawa, Satoshi Katsube, Daisuke Unabara, Tasuku Hamaguchi, Keisuke Kawakami, Koji Yonekura, Akihide Hibara, Atsushi Wakamiya, Hiroshi Uji‐I, Hitoshi Kasai   +18 more
wiley   +1 more source

root morphological traits and Ks

The data pertains to soil saturated hydraulic conductivity and root morphological traits, including:Soil saturated hydraulic conductivity (Ks)​​​,Root length density (RLD), Root surface area density (RSD),​​​ Root weight density (RWD)​​ and Root volume ...
Chen, Lichen
core   +1 more source

Species`differences in morphological traits related to feeding biology.

, 2015
*diagnostic character between N. krameri A and N. krameri B.Species`differences in morphological traits related to feeding biology.
Valerija Zakšek (474599), Žiga Fišer (777321), Florian Altermatt (82469), Tea Knapič (777322), Cene Fišer (474600)   +4 more
core   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Genetic analysis of breeding-related traits in Brassica rapa [PDF]

, 2009
Brassica rapa is an important crop with a variety of forms, and a wide distribution in the world. It is used as oil seed and vegetable crop and a valuable source of diverse health-promoting metabolites.
Bagheri, H.
core  

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Correlations between agro-morphological traits.

, 2018
Plots of the coefficients of correlation calculated between agro-morphological traits per pairs. For each graph 45 correlation coefficients associated to 45 pairs of agro-morphological traits obtained in different conditions or at different dates were ...
Sixtine Passot (5896454), Daniel Foncéka (5648635), Pascal Gantet (209330), Prakash Gangashetty (5896460), Laurent Laplaze (140124), Ndjido Ardo Kane (4050430), Vincent Vadez (619039), Laurent Cournac (2080996), Yves Vigouroux (219609), Charles Tom Hash (5896463), Eyanawa Akata (5896457), Marilyne Debieu (415078), Bassirou Sine (5896451), Alexandre Grondin (5576216)   +13 more
core   +1 more source