Results 201 to 210 of about 1,633,995 (265)

Developing a strain‐dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud   +3 more
wiley   +1 more source

A comprehensive dataset of morphological traits for Indian climbers. [PDF]

open access: yesData Brief
Pujari A   +10 more
europepmc   +1 more source

Animal stroke models and outcome evaluation: A review

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba   +2 more
wiley   +1 more source

Histological analysis of the spatio‐temporal development of porcine knee cartilage in embryonic and early postnatal stages

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study dynamically charts the developmental process of the knee joint cartilage from the embryonic stage through to postnatal life, revealing key developmental events including the origin of knee joint development, chondrification, primary ossification, secondary ossification, formation of the cartilage cancal, and formation of the growth plate. It
Yan Nie   +9 more
wiley   +1 more source

Optimizing Electrode Design for Functional Activation of Human Pluripotent Stem Cell‐Derived Cardiomyocytes

open access: yesAdvanced NanoBiomed Research, EarlyView.
Electrical stimulation of human pluripotent stem cell‐derived cardiomyocytes is systematically investigated as a function of electrode material and configuration. Stimulation efficiency is found to be governed predominantly by electrode geometry, with increased electrode area and proximity to cells enabling more effective pacing.
Gustavo Ramirez‐Calderon   +12 more
wiley   +1 more source

Development of Biocatalysts Based on Lipase B From Candida antarctica Immobilized on Magnetic Poly(Styrene‐Co‐Divinylbenzene) for Application in Esterification Reactions

open access: yesJournal of Applied Polymer Science, EarlyView.
Magnetic biocatalysts can be recovered from high‐viscosity reaction media, such as those used in esterification, via magnetic attraction, thereby streamlining the bioprocess and reducing costs. This work builds on prior studies by providing additional data on how particle morphology influences immobilization parameters and by further exploring ...
Sabrina S. Teixeira   +7 more
wiley   +1 more source

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