Results 141 to 150 of about 242,571 (301)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Evolving generalist controllers to handle a wide range of morphological variations [PDF]

Neuro-evolutionary methods have proven effective in addressing a wide range of tasks. However, the study of the robustness and generalizability of evolved artificial neural networks (ANNs) has remained limited. This has immense implications in the fields
Yaman, Anil; id_orcid, Yaman, Anil, Triebold, Corinna   +2 more
core   +2 more sources

Morphological variation and phylogenetic position of Vatica rassak ( Dipterocarpaceae ) based on the trn L- trn F region

Plant and Fungal Systematics
Vatica rassak is one of the most exploited species of the genus Vatica for its wood and resin. The species exhibits high morphological variations across their range of distribution that crosses the border of the Wallace’s line.
Kusumadewi Sri Yulita, Elisa Andriyani, Arida Susilowati, Henti Hendalastuti Rachmat, Nawwall Arrofaha, Susila Susila, Asep Hidayat, Irsyad Kamal   +7 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Morphological variations of the mandibular condyle as assessed from panoramic radiographic images: a literature review [PDF]

Objectives: This literature review aims to analyze the morphological variations of the mandibular condyle as observed in panoramic radiographic images.
Masyrifah, Nurul, Yunus, Barunawaty
core  

Morphological and Genetic Variation of Filopaludina javanica (von dem Busch, 1844) (Gastropoda: Viviparidae) from Madura Island, Indonesia

Hayati Journal of Biosciences
Filopaludina javanica (von dem Busch, 1844) is a freshwater gastropod species in the Viviparidae family. Filopaludina javanica is widely distributed in freshwater waters in Java (including Madura), Sulawesi, Sumatra, Borneo, Papua, Thailand, and Vietnam.
Hafiidh Haqqu Nugroho, Reni Ambarwati, Nur Rohmatin Isnaningsih, Dwi Anggorowati Rahayu   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source