Results 101 to 110 of about 4,305,036 (352)

On the processing of agreement morphology [PDF]

, 2018
The paper deals with the role played by morphology in core syntax within a generative minimalist framework: more specifically it deals with the theory of valuation of agreement or phi-features (that is, person and number features) and the valuation of ...
Castillo, Concha, Castillo-Orihuela, Concepcion   +1 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Astrocyte morphology

Trends in Cell Biology
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal feature of astrocytes is their complex and visually enchanting morphology, referred to as bushy, spongy, and star-like. A central precept of this review is that such complex morphological shapes evolved to allow astrocytes to contact and signal with diverse ...
Baldwin, Katherine T, Murai, Keith K, Khakh, Baljit S   +2 more
openaire   +4 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Thin-Film Metamaterials called Sculptured Thin Films

, 2010
Morphology and performance are conjointed attributes of metamaterials, of which sculptured thin films (STFs) are examples. STFs are assemblies of nanowires that can be fabricated from many different materials, typically via physical vapor deposition onto
A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Lakhtakia, A. Shalabaney, A.C. Popta van, A.L. Elias, B. Dick, D.-X. Ye, D.-X. Ye, E. Ertekin, E. Schubert, F. Wang, F. Wang, F. Wang, F. Zhang, F. Zhang, G.K. Kiema, H. Tan, I. Hodgkinson, I.J. Hodgkinson, I.J. Hodgkinson, I.J. Hodgkinson, J.A. Polo, J.A. Polo Jr, J.A. Polo Jr, J.A. Reyes, J.A. Sherwin, J.A. Sherwin, J.A. Sherwin, J.B. Geddes III, J.C. Sit, J.J. Steele, J.J. Steele, J.M. Nieuwenhuizen, J.N. Broughton, K. Robbie, K. Robbie, K. Robbie, K.D. Harris, M. Malac, M. Suzuki, M.A. Motyka, M.A. Motyka, M.C. Demirel, M.C. Demirel, M.O. Jensen, M.W. Horn, M.W. Horn, M.W. Seto, N. Verplanck, N.O. Young, P.C.P. Hrudey, R. Messier, R. Messier, R. Messier, R. Walser, R.J. Carey, R.J. Martín-Palma, R.J. Martín-Palma, R.J. Martín-Palma, S. Pursel, S. Tsoi, S.M. Pursel, T. Motohiro, T.G. Mackay, V.C. Venugopal, V.C. Venugopal, Y. Inoue, Y. Zhou, Y.J. Park   +83 more
core   +1 more source

Philosophical Morphology

Disputatio philosophica : International Journal on Philosophy and Religion, 2009
In the paper authors present, examine, and test elements of the vital idea of the philosophical morphology as a method and a technique of philosophical investigation. The paper consists of some applications mostly concerning the method applied by L. Wittgenstein in PI and related later works, and of a series of examples concerning daily phenomena.
Lukin, Josip, Krkač, Kristijan
openaire   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Morphological Predictors of Restenosis After Coronary Stenting in Humans [PDF]

, 2002
Andrew Farb, Deena K. Weber, Frank D. Kolodgie, Allen Burke, Renu Virmani   +4 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Understanding Genomic Evolution of Olfactory Receptors through Fractal and Mathematical Morphology [PDF]

, 2011
Fractals and Mathematical Morphology are immensely used to study many problems in different branches of science and technology including the domain of Biology. There are many more unrevealed facts and figures of genes and genome in Computational Biology.
Arunava Goswami, B. S. Dayasagar, Pabitra Pal Choudhury, Ranita Guha, Shantanav Chakraborty, Sk. Sarif Hassan   +5 more
core   +1 more source