Results 81 to 90 of about 3,855,608 (296)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Potentiating Effect of Nitric Oxide Donor on Antitumor Activity of Doxorubicin in Glioblastoma-Bearing Rats

open access: yesАнтибиотики и Химиотерапия, 2020
The objective of the study was to investigate the influence of the NO donor nitroglycerin (NG) on the antitumour effect of doxorubicin (Dox) in rats with the intracranially implanted 101.8 glioblastoma. Materials and methods.
A. I. Alekseeva   +4 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis

open access: yesScientific Reports, 2017
Despite the associations between diabetic complications and vascular endothelial dysfunction, a direct therapeutic method targeting endothelial dysfunction remains poorly characterized.
Kumiko Taguchi   +5 more
doaj   +1 more source

Morphology of Mock SDSS Catalogues

open access: yes, 2003
We measure the geometry, topology and morphology of the superclusters in mock SDSS catalogues prepared by Cole et al.(1998). The mock catalogues refer to $\tau$CDM and $\L$CDM {\em flat} cosmological models and are populated by galaxies so that these act
Abazajian   +33 more
core   +1 more source

A Morphology-Aware Network for Morphological Disambiguation

open access: yesProceedings of the AAAI Conference on Artificial Intelligence, 2016
Agglutinative languages such as Turkish, Finnish andHungarian require morphological disambiguation beforefurther processing due to the complex morphologyof words. A morphological disambiguator is usedto select the correct morphological analysis of a word.Morphological disambiguation is important because itgenerally is one of the first ...
Yildiz, Eray   +4 more
openaire   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration

open access: yesStem Cells International, 2017
Adequate vascularization, a restricting factor for the survival of engineered tissues, is often promoted by the addition of stem cells or the appropriate angiogenic growth factors.
Petra Hilkens   +5 more
doaj   +1 more source

Hydrological Interpretation of Basin Morphology [PDF]

open access: yes, 1978
Completion Report OWRT Agreement No. 14-31-0001-5002 OWRT Project A-049-ALASHydrologic processes in a particular basin are governed by three groups of factors: input regimes of mass and energy, the nature of mass and energy transfer and ...
Fox, John D.
core  

Morphological Analysis [PDF]

open access: yes, 1999
Chapter 12 In the previous chapters, we have seen that a lot of information about the potential tags of tokens in a text is found by lexicon lookup. Another, often complementary source of information is morphological analysis, i.e. the process of decomposing words into their constituents. The information about the individual constituents can be used to
openaire   +2 more sources

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