Results 71 to 80 of about 2,701,117 (260)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Introducing morphology

open access: yes, 2012
Morphology is the study of how words are put together. A lively introduction to the subject, this textbook is intended for undergraduates with relatively little background in linguistics. Providing data from a wide variety of languages, it includes hands-
Rochelle Lieber
core  

Potentiating Effect of Nitric Oxide Donor on Antitumor Activity of Doxorubicin in Glioblastoma-Bearing Rats

open access: yesАнтибиотики и Химиотерапия, 2020
The objective of the study was to investigate the influence of the NO donor nitroglycerin (NG) on the antitumour effect of doxorubicin (Dox) in rats with the intracranially implanted 101.8 glioblastoma. Materials and methods.
A. I. Alekseeva   +4 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Potential Cytotoxic Effect of the Drug Interaction Between 5-FU and Carcinogens: Histopathological Evidence in an In Vivo Murine Model

open access: yesProceedings
Introduction: 5-fluorouracil (5-FU) is the standard chemotherapeutic agent for treating squamous cell carcinoma (SCC) [...]
José Carlos E. Queiroz   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Lakota Morphology Problem Set

open access: yes, 2010
A introductory problem set in morphology using Lakota (Siouan). Set includes a word and pdf version, but no answer key. Note that the word document uses the old SIL Doulos IPA93 font.This item is part of a collection of learning objects developed for ...
Fountain, Amy
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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