Results 71 to 80 of about 3,855,608 (296)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

miRNAs as Influencers of Cell–Cell Communication in Tumor Microenvironment

Cells, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Ilaria Conti, Gabriele Varano, Carolina Simioni, Ilaria Laface, Daniela Milani, Erika Rimondi, Luca M. Neri   +6 more
doaj   +1 more source

Advances in Morphological Theory: Construction Morphology and Relational Morphology

Annual Review of Linguistics, 2022
In recent years, construction-based approaches to morphology have gained ground in the research community. This framework is characterized by the assumption that the mental lexicon is extensive and richly structured, containing not only a large number of stored words but also a wide variety of generalizations in the form of schemas.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Therapeutic Effect of Antitumor Drugs Erufosine and Doxorubicin on the Metastatic Process in the Testes of Hamsters with Graffi Myeloid Tumor. Morphometric and Histological Studies

Клиническая онкогематология
Aim. The goal of the current study is directed to investigate the therapeutic effect of erufosine (ЕРС3) alone, as well as in combination with doxorubicin (DOX) on the development of metastases in the testes in an experimental model of transplantable ...
Iliana Najdenova Ilieva, I. V. Sainova, R. A. Toshkova, A. K. Georgieva, V. N. Nanev, R. D. Tzoneva   +5 more
doaj   +1 more source

Natural Morphology

, 2018
Natural Morphology offers a fairly elaborated model for analyzing and interpreting morphological facts, which heavily relies on the one hand on a semiotic foundation of the linguistic sign and on the other on a comprehensive understanding of the cognitive, typological, and system-specific aspects of natural languages.
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Effects of tidally enhanced stellar wind on the horizontal branch morphology of globular clusters

, 2012
Metallicity is the first parameter to influence the horizontal branch (HB) morphology of globular clusters (GCs). It has been found, however, that some other parameters may also play an important role in affecting the morphology.
Chen, Xue-Fei, Han, Z., Lei, Zhen-Xin, Zhang, Feng-Hui   +3 more
core   +1 more source