Results 51 to 60 of about 2,387,418 (315)
ProceedingsIntroduction: The low financial profitability of the treatment of neglected diseases, such as cutaneous leishmaniasis (CL), results in outdated treatments with limited efficacy and high toxicity [...]
Maria G. da Silva +6 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
3D Cell Culture Models for the Study of New Anti-Inflammatory Drugs: Toxicity and Cell Viability
ProceedingsIntroduction: In Brazil, pressure ulcer wounds have a significant impact on public health [...]
Juliano C. T. T. Almeida +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Towards a socio-ecological spatial morphology : integrating elements of urban morphology and landscape ecology [PDF]
, 2019 The recent shift towards greater emphasis on biodiversity and urban ecosystems has increased the need for greater understanding of the green areas in cities as ecological environments.
Barthel, Stephan, +2 more
core
Periodontal disease and osteoporosis association and mechanisms: A review of the literature
Brazilian Journal of Oral Sciences, 2015 Periodontitis and osteoporosis, diseases that affect millions of people in world, present bone loss as common hallmark. Prevalence of both osteoporosis and tooth loss increase with advancing age in both women and men. Systemic bone loss has been proposed
Marcelo R. Marques +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2017 To establish if foliar herbivory causes changes in floral morphology and rewards that could alter floral visitation, we selected another 30 pairs of plants (15 pin and 15 thrum) of P. angustifolia.
Katja Poveda (601846) +3 more
core +1 more source
ScientificaThe ban on the use of antibiotics in animal husbandry encourages an active search for highly effective alternatives with additional properties, one of which is ultrafine particles (UFP) of metallic nature.
Daniil E. Shoshin +5 more
doaj +1 more source
European Journal of Histochemistry, 2009 Phosphoinositide 3-kinases (PI 3-kinases), a class of enzymes implicated in growth factor-induced mitogenic response and many other intracellular signalling pathways, act by phosphorylation at the D-3’-OH position of the myo-inositol ring of ...
M. Marchisio +4 more
doaj +1 more source