Results 31 to 40 of about 2,701,117 (260)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The damping and structural properties of dragonfly and damselfly wings during dynamic movement
Lietz, Rajabi and colleagues investigate the physiological and structural components of damping in insect wings. Notably, flight muscles and hemolyph appear to have no direct involvement in wing damping, compared to the function of the wing hinge.
Carina Lietz +3 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
THE EFFECT OF ALLOXAN-INDUCED HYPERGLYCEMIA ON THE RENAL CORTEX
About 422 million people in the world suffer from diabetes mellitus. Among diseases, diabetes ranks third, and among endocrine disorders, it ranks first. Some issues concerning the pathogenesis of this disease are unclear.
Sofia Frolova +2 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Morphology is a lively, comprehensive introduction to current morphological theory and analysisxvii, 382 hlm; 23,5 x 15,5 ...
Francis Katamba, Jhon stonham
core +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Introduction: The low financial profitability of the treatment of neglected diseases, such as cutaneous leishmaniasis (CL), results in outdated treatments with limited efficacy and high toxicity [...]
Maria G. da Silva +6 more
doaj +1 more source

