Results 141 to 150 of about 2,387,418 (315)

Systematics of grammitid ferns (Polypodiaceae): using morphology and plastid sequence data to resolve the circumscriptions of Melpomene and the polyphyletic genera Lellingeria and Terpsichore. [PDF]

open access: yes, 2010
Systematics of grammitid ferns (Polypodiaceae): using morphology and plastid sequence data to resolve the circumscriptions of Melpomene and the polyphyletic genera Lellingeria and ...

core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Faithfulness and identity in prosodic morphology [PDF]

open access: yes, 1999
This article is largely based on the more extensive study McCarthy & Prince (1995), but includes significant further analysis of the typology of reduplication-phonology interactions and new discussion of the connection between base-reduplicant identity ...
McCarthy, John J, Prince, Alan
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Marked uses of tense/aspect morphology and situation type [PDF]

open access: yes, 2013
In this study explanations are sought for the often reported associations in child language between tense/aspect morphology and situation type. The study is done on the basis of adult-adult data, child language and input language to the children.
Boland, Annerieke
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Functional morphology of marsupial moles (Marsupialia: Notoryctidae) [PDF]

open access: yes, 2006
Marsupial moles (genus Notoryctes) are the most highly specialised burrowing marsupials. The specialisations of the appendicular musculo-skeletal system of the marsupial moles are extensive and widespread; the major alterations are concentrated in, but ...
Warburton, N.M.
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

A quantitative study of the relationships between morphology, physiology and geldanamycin synthesis in submerged cultures of Streptomyces hygroscopicus var. geldanus [PDF]

open access: yes, 2008
Microbially produced secondary metabolites such as antibiotics have tremendous economic importance. However, most are produced by filamentous organisms which exhibit diverse growth patterns presenting challenges for industrial fermentation.
Dobson, Lynne
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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