Results 1 to 10 of about 1,092,878 (307)

Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae [PDF]

, 2019
Sterols are essential lipids, involved in many biological processes. In Saccharomyces cerevisiae, the enzymes of the ergosterol biosynthetic pathway (Erg proteins) are localized in different cellular compartments.
Balliano, Gianni, Bianchi, Michele Maria, Cirigliano, Angela, Macone, Alberto, Negri, Rodolfo, Oliaro-Bosso, Simonetta, Rinaldi, Teresa   +6 more
core   +2 more sources

Inhibitory effect of O-propargyllawsone in A549 lung adenocarcinoma cells

BMC Complementary Medicine and Therapies, 2023
Background Lung cancer is the deadliest type of cancer in the world and the search for compounds that can treat this disease is highly important. Lawsone (2-hydroxy-1,4-naphtoquinone) is a naphthoquinone found in plants from the Lawsone genus that show a
Edmilson Willian Propheta dos Santos, Rauan Cruz de Sousa, Mariana Nobre Farias de Franca, Jileno Ferreira Santos, Flaviano Melo Ottoni, Raquel Geralda Isidório, Waldecy de Lucca Junior, Ricardo José Alves, Ricardo Scher, Cristiane Bani Corrêa   +9 more
doaj   +1 more source

SynBio in 3D: The first synthetic genetic circuit as a 3D printed STEM educational resource

Frontiers in Education, 2023
Synthetic biology is a new area of science that operates at the intersection of engineering and biology and aims to design and synthesize living organisms and systems to perform new or improved functions.
Heloísa Oss Boll, Matheus de Castro Leitão, Aisel Valle Garay, Ana Carolina Campos Batista, Sophia Garcia de Resende, Leonardo Ferreira da Silva, Viviane Castelo Branco Reis, Emerson Monteiro Vieira, Cíntia Marques Coelho   +8 more
doaj   +1 more source

An alternative pattern of head expansion during feeding in cichlids

Communications Biology
Specialized feeding methods evolved repeatedly from a suction-feeding strategy in cichlids. How algae-eaters altered their suction mechanics to transport detached algae efficiently, and how this may hinder capturing larger prey, remains unclear. Here, we
Jana De Ridder, Vincent Dujardin, Julia Camacho Garcia, Wilson Sawasawa, Peter Aerts, Hannes Svardal, Sam Van Wassenbergh   +6 more
doaj   +1 more source

Simplifying Biology Vocabulary via Morphology

The American Biology Teacher, 2023
In all fields of biology, understanding technical terminology is a challenge for students. In many cases, this may distract them from focusing on fundamental processes and concepts. Across the biology subfields, much of the vernacular shares similar etymology and morphology.
openaire   +1 more source

Anti-proliferative and pro-apoptotic activity of glycosidic derivatives of lawsone in melanoma cancer cell

BMC Cancer, 2021
Background Melanoma is a malignant cancer that affects melanocytes and is considered the most aggressive skin-type cancer. The prevalence for melanoma cancer for the last five year is about one million cases.
Mariana Nobre Farias de Franca, Raquel Geralda Isidório, João Henrique Oliveira Bonifacio, Edmilson Willian Propheta dos Santos, Jileno Ferreira Santos, Flaviano Melo Ottoni, Waldecy de Lucca Junior, Ricardo Scher, Ricardo José Alves, Cristiane Bani Corrêa   +9 more
doaj   +1 more source

Computational modeling to elucidate molecular mechanisms of epigenetic memory

, 2015
How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin statuses?
Alsing, Andrews, Ang, Angel, Arnold, Bannister, Barth, Beisel, Benecke, Bhattacharya, Binder, Black, Buscaino, Bushey, Canzio, Cowieson, David-Rus, Dayarian, Deal, Dodd, Fonseca, Freddolino, Gaffney, Grauffel, Greer, Grewal, Grigoryev, Hanna, Hathaway, Henikoff, Herranz, Hodges, Jacobs, Korolev, Korolev, Kouzarides, Ku, Kulaeva, Lin, Margreitter, Margueron, Mendenhall, Muller, Papp, Pasque, Peinado, Piana, Potoyan, Prohaska, Raghavan, Rohlf, Sanbonmatsu, Sanli, Schwab, Schwammle, Sedighi, So, Sontag, Steffen, Takahashi, Teif, Thon, Wocjan, Xu, Yang, Yuan, Zee, Zhang, Zhang   +68 more
core   +1 more source

Transmission-Blocking Vaccines for Canine Visceral Leishmaniasis: New Progress and Yet New Challenges

Vaccines, 2023
Dogs with visceral leishmaniasis play a key role in the transmission cycle of Leishmania infantum to humans in the urban environment. There is a consensus regarding the importance of developing a vaccine to control this disease.
Jaqueline Costa Leite, Ana Alice Maia Gonçalves, Diana Souza de Oliveira, Lucilene Aparecida Resende, Diego Fernandes Vilas Boas, Helen Silva Ribeiro, Diogo Fonseca Soares Pereira, Augusto Ventura da Silva, Reysla Maria da Silveira Mariano, Pedro Campos Carvalhaes Reis, Eiji Nakasone Nakasone, João Carlos França-Silva, Alexsandro Sobreira Galdino, Paulo Ricardo de Oliveira Paes, Marília Martins Melo, Edelberto Santos Dias, Miguel Angel Chávez-Fumagalli, Denise da Silveira-Lemos, Walderez Ornelas Dutra, Rodolfo Cordeiro Giunchetti   +19 more
doaj   +1 more source

3D mesh processing using GAMer 2 to enable reaction-diffusion simulations in realistic cellular geometries

, 2019
Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed geometries ...
Amaro, Rommie E., de La Beaumelle, Nils Angliviel, Holst, Michael J., Laughlin, Justin G., Lee, Christopher T., McCammon, J. Andrew, Ramamoorthi, Ravi, Rangamani, Padmini   +7 more
core   +1 more source

TICAL - a web-tool for multivariate image clustering and data topology preserving visualization [PDF]

, 2011
In life science research bioimaging is often used to study two kinds of features in a sample simultaneously: morphology and co-location of molecular components.
Abouna, Sylvie, Khan, Michael, Kölling, Jan, Langenkämper, Daniel, Nattkemper, Tim W., Niehaus, Karsten   +5 more
core