Results 41 to 50 of about 1,103,016 (356)

SynBio in 3D: The first synthetic genetic circuit as a 3D printed STEM educational resource

Frontiers in Education, 2023
Synthetic biology is a new area of science that operates at the intersection of engineering and biology and aims to design and synthesize living organisms and systems to perform new or improved functions.
Heloísa Oss Boll, Matheus de Castro Leitão, Aisel Valle Garay, Ana Carolina Campos Batista, Sophia Garcia de Resende, Leonardo Ferreira da Silva, Viviane Castelo Branco Reis, Emerson Monteiro Vieira, Cíntia Marques Coelho   +8 more
doaj   +1 more source

Inhibitory effect of O-propargyllawsone in A549 lung adenocarcinoma cells

BMC Complementary Medicine and Therapies, 2023
Background Lung cancer is the deadliest type of cancer in the world and the search for compounds that can treat this disease is highly important. Lawsone (2-hydroxy-1,4-naphtoquinone) is a naphthoquinone found in plants from the Lawsone genus that show a
Edmilson Willian Propheta dos Santos, Rauan Cruz de Sousa, Mariana Nobre Farias de Franca, Jileno Ferreira Santos, Flaviano Melo Ottoni, Raquel Geralda Isidório, Waldecy de Lucca Junior, Ricardo José Alves, Ricardo Scher, Cristiane Bani Corrêa   +9 more
doaj   +1 more source

Testis and brown adipose tissue xenografts from yellowish myotis (Myotis levis)

Reproduction and Fertility, 2022
Yellowish myotis present a seasonal reproduction, influenced by rainfall distribution, in which the testis mass, germ cell composition, and brown adipose tissue (B.A.T.) mass change along the reproductive stages.
Talita De Oliveira Farias, André Felipe Almeida Figueiredo, Natalia Teixeira Wnuk, Sônia Aparecida Talamoni, Guilherme Mattos Jardim Costa   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

An alternative pattern of head expansion during feeding in cichlids

Communications Biology
Specialized feeding methods evolved repeatedly from a suction-feeding strategy in cichlids. How algae-eaters altered their suction mechanics to transport detached algae efficiently, and how this may hinder capturing larger prey, remains unclear. Here, we
Jana De Ridder, Vincent Dujardin, Julia Camacho Garcia, Wilson Sawasawa, Peter Aerts, Hannes Svardal, Sam Van Wassenbergh   +6 more
doaj   +1 more source

Simplifying Biology Vocabulary via Morphology

The American Biology Teacher, 2023
In all fields of biology, understanding technical terminology is a challenge for students. In many cases, this may distract them from focusing on fundamental processes and concepts. Across the biology subfields, much of the vernacular shares similar etymology and morphology.
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Anti-proliferative and pro-apoptotic activity of glycosidic derivatives of lawsone in melanoma cancer cell

BMC Cancer, 2021
Background Melanoma is a malignant cancer that affects melanocytes and is considered the most aggressive skin-type cancer. The prevalence for melanoma cancer for the last five year is about one million cases.
Mariana Nobre Farias de Franca, Raquel Geralda Isidório, João Henrique Oliveira Bonifacio, Edmilson Willian Propheta dos Santos, Jileno Ferreira Santos, Flaviano Melo Ottoni, Waldecy de Lucca Junior, Ricardo Scher, Ricardo José Alves, Cristiane Bani Corrêa   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source