Results 141 to 150 of about 1,090,581 (353)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

SHIP identifies genomic safe harbors in eukaryotic organisms using genomic general feature annotation

Scientific Reports
Integrating foreign genes into loci, allowing their transcription without affecting endogenous gene expression, is the desirable strategy in genomic engineering.
Matheus de Castro Leitão, Letícia Sousa Cabral, Luiza Cesca Piva, Pedro Felipe de Sousa Queiroz, Taísa Godoy Gomes, Rosângela Vieira de Andrade, Ana Laura Alfonso Perez, Karen Letycia Rodrigues de Paiva, Sônia Nair Báo, Viviane Castelo Branco Reis, Lídia Maria Pepe Moraes, Roberto Coiti Togawa, Leila Maria Gomes Barros, Fernando Araripe Gonçalves Torres, Georgios Joannis Pappas Júnior, Cíntia Marques Coelho   +15 more
doaj   +1 more source

New Approaches to the Prevention of Visceral Leishmaniasis: A Review of Recent Patents of Potential Candidates for a Chimeric Protein Vaccine

Vaccines
The development of prophylactic vaccines is important in preventing and controlling diseases such as visceral leishmaniasis (VL), in addition to being an economic measure for public health. Despite the efforts to develop a vaccine against human VL caused
Diana Souza de Oliveira, Maykelin Fuentes Zaldívar, Ana Alice Maia Gonçalves, Lucilene Aparecida Resende, Reysla Maria da Silveira Mariano, Diogo Fonseca Soares Pereira, Ingrid dos Santos Soares Conrado, Mariana Amália Figueiredo Costa, Daniel Ferreira Lair, Diego Fernandes Vilas-Boas, Eiji Nakasone Nakasone, Ingrid de Sousa Ameno, Wanessa Moreira Goes, Denise Silveira-Lemos, Alexsandro Sobreira Galdino, Ronaldo Alves Pinto Nagem, Walderez Ornelas Dutra, Rodolfo Cordeiro Giunchetti   +17 more
doaj   +1 more source

Comparative morphology, biology and phylogeny of terminal-instar larvae of the European species of Toryminae (Hym., Chalcidoidea, Torymidae) parasitoids of gall wasps (Hym. Cynipidae) [PDF]

, 2008
José F. Gómez, J. L. Nieves‐Aldrey, María Hernández Nieves   +2 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Larval morphology of the antlion Neuroleon microstenus (McLachlan, 1898) (Neuroptera, Myrmeleontidae), with notes on larval biology

, 2010
Dušan Devetak, Saška Lipovšek, Maria-Anna Pabst   +2 more
openalex   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Morphological and molecular characteristics of Milandanielia intermedia (Feider, 1950) (Trombidiformes: Microtrombidiidae) with data on its biology and ecology

, 2015
Magdalena Felska, Joanna Mąkol
openalex   +2 more sources

Discovery of a New Gall-Inducing Species in the Inquiline Tribe Synergini (Hymenoptera: Cynipidae): Inconsistent Implications from Biology and Morphology [PDF]

, 2011
Yoshihisa Abe, Tatsuya Ide, Nakatada Wachi   +2 more
openalex   +1 more source