The developmental cell biology of Trypanosoma brucei [PDF]
, 2005 Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R
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Perspectives on the mathematics of biological patterning and morphogenesis [PDF]
Journal of the Mechanics and Physics of Solids, 99, 192-210, 2017, 2016 A central question in developmental biology is how size and position are determined. The genetic code carries instructions on how to control these properties in order to regulate the pattern and morphology of structures in the developing organism. Transcription and protein translation mechanisms implement these instructions. However, this cannot happen
arxiv +1 more source
Plant genetic reseources: effective utilization [PDF]
, 2010 Characterizing better understanding the genome organization and differentiating identity of genotypes based on their morphology and genome characteristics are vital determinants in their commercialization, management of germplasm repositories, and ...
Budak, Hikmet
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A computational framework for the morpho-elastic development of molluskan shells by surface and volume growth [PDF]
PLOS Computational Biology 15(7): e1007213; 2019, 2019 Mollusk shells are an ideal model system for understanding the morpho-elastic basis of morphological evolution of invertebrates' exoskeletons. During the formation of the shell, the mantle tissue secretes proteins and minerals that calcify to form a new incremental layer of the exoskeleton.
arxiv +1 more source
Collective Cell Mechanics of Small-Organoid Morphologies [PDF]
Nat. Commun. 11, 3805 (2020), 2019 The study of organoids, artificially grown cell aggregates with the functionality and small-scale anatomy of real organs, is one of the most active areas of research in biology and biophysics, yet the basic physical origins of their different morphologies remain poorly understood.
arxiv +1 more source
Atlas Toolkit: Fast registration of 3D morphological datasets in the absence of landmarks [PDF]
, 2016 Image registration is a gateway technology for Developmental Systems Biology, enabling computational analysis of related datasets within a shared coordinate system.
A Schohl +11 more
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Molecule-Morphology Contrastive Pretraining for Transferable Molecular Representation [PDF]
arXiv, 2023 Image-based profiling techniques have become increasingly popular over the past decade for their applications in target identification, mechanism-of-action inference, and assay development. These techniques have generated large datasets of cellular morphologies, which are typically used to investigate the effects of small molecule perturbagens. In this
arxiv
Gonad development and reproduction in the monoecious species Chlorophthalmus agassizi (Actinopterygii: Aulopiformes: Chlorophthalmidae) from the Sardinian Waters (Central-Western Mediterranean) [PDF]
, 2010 Background. The shortnose greeneye, Chlorophthalmus agassizi Bonaparte, 1840, is a species with a circumglobal distribution and is among the most abundant commercial fishes in some Mediterranean areas.
Cabiddu S, Cau A, Follesa MC, Porcu C
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Nuclear Morphology and the Biology of Cancer Cells [PDF]
Acta Cytologica, 2020 Background: For more than a century, diagnostic pathologists have used morphologic abnormalities of the nucleus as essential diagnostic features to distinguish benign from malignant cells. These features include nuclear enlargement and increased nuclear-to-cytoplasmic ratio, nuclear membrane irregularities, hyperchromasia, and abnormal chromatin ...
openaire +2 more sources
The Interplay among PINK1/PARKIN/Dj-1 Network during Mitochondrial Quality Control in Cancer Biology: Protein Interaction Analysis [PDF]
, 2018 PARKIN (E3 ubiquitin ligase PARK2), PINK1 (PTEN induced kinase 1) and DJ-1 (PARK7) are proteins involved in autosomal recessive parkinsonism, and carcinogenic processes.
Lucas, Millikin, Narendra, Santel, Zhang
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