Results 101 to 110 of about 115,083 (267)

Diversity of seven wild Zingiberaceae from Meru Betiri National Park, Indonesia

open access: yesJurnal Ilmu Dasar
Zingiberaceae, the largest family within the order Zingiberales, comprises numerous species of economic and medicinal importance. However, members of this family often exhibit similar morphological characteristics, making species identification in their ...
Dwi Setyati   +3 more
doaj   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng   +17 more
wiley   +1 more source

Pendugaan Jarak Genetik Kelinci (Hyla, Hycole, Hycolex NZW, Rex, dan Satin) Melalui Analisis Morfometrik (ESTIMATION OF RABBIT GENETIC DISTANCE (HYLA, HYCOLE, HYCOLEXNZW, NZW, REX AND SATIN) THROUGH MORPHOMETRIC ANALYSIS)

open access: yesJurnal Veteriner, 2016
The observation on morphological body conformation of Hyla (CC), Hycole (FF), HycolexNZW (FN),New Zealand White (NN), Rex (RR), and Satin (SS) were carried out to determine estimation of mahalanobisgenetic distance.
Bram Brahmantiyo   +2 more
doaj  

Morphometric characterization using a multivariate approach: The case of cattle breeds raised on traditional cattle farms in northern Côte d’Ivoire

open access: yesGenetic Resources
One of the major constraints to cattle breeding development in Côte d’Ivoire is the limited knowledge of the genetic composition of the national herd.
Franck Armand Désiré Yao   +10 more
doaj   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

open access: yesAdvanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang   +12 more
wiley   +1 more source

Mn/Zn Bimetallic MOF‐Integrated Hydrogel Alleviates Excessive Mitochondrial Fission in BMSCs to Promote Osteoporotic Jawbone Repair

open access: yesAdvanced Science, EarlyView.
Excessive reactive oxygen species (ROS) and chronic inflammation impair bone marrow‐derived mesenchymal stem cells (BMSCs), contributing to poor healing in osteoporotic jawbone defect. The gelatin methacryloyl hydrogel loaded with manganese‐doped zeolitic imidazolate framework (Mn‐ZIF‐8@GelMA) promotes regeneration through redox regulation and ...
Xiayue Jin   +6 more
wiley   +1 more source

RBMS1 Contributes to Early Arteriovenous Fistula Neointimal Remodeling Through Modulation of VSMC Phenotypic Responses

open access: yesAdvanced Science, EarlyView.
Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li   +14 more
wiley   +1 more source

Reference Values for Postmortem Examination of the Heart in the Macropod (Macropodidae) and Koala (Phascolarctidae)

open access: yesAnimals
Morphometric cardiac reference values are reported for macropods and koalas (Phascolarctos cinereus). Body weight (BW), heart weight (HW), left ventricle (LV) wall, interventricular septum (S), right ventricle (RV) wall thickness, and LV+S and RV weights
Ella Cousins   +4 more
doaj   +1 more source

Serial H&E Pathology Reveals Progression‐Associated Nuclear Size Drift as a Longitudinal Digital Readout of Bladder Cancer Evolution

open access: yesAdvanced Science, EarlyView.
Routine serial H&E specimens from bladder cancer are converted into paired T0/T1 digital pathology readouts of tumor evolution. Progression is associated with longitudinal nuclear drift, with nuclear size‐related changes most evident in the independent confirmation cohort, alongside a broader spatial burden of increased nuclear area and biological ...
Xing Liu   +14 more
wiley   +1 more source

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