Results 101 to 110 of about 485,703 (403)

ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis

open access: yesAdvanced Science, EarlyView.
Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang   +13 more
wiley   +1 more source

The adaptability of Garut sheep grazing on oil palm and rubber plantations in tropical conditions of Indonesia [PDF]

open access: yesVeterinary World
Background and Aim: The productivity of sheep in humid tropical plantation areas relies on their ability to adapt. Oil palm plantations serve as potential grazing lands for livestock.
Bess Tiesnamurti   +7 more
doaj   +1 more source

Morphometric, meristics and comparative studies of Chrysichthys nigrodigititus (Lacepede) from Lagos Lekki and Badagry Lagoons, Lagos State, south west Nigeria [PDF]

open access: yes, 2005
Morphometric measurements, meristic counts and comparative studies of Chrysicthys nigrodigitatus samples from Lagos, Lekki, and Badagry Lagoons was carried out to determine the amount of variation among the species from the different locations using ...
Ajado, E.O.   +2 more
core  

Assessing the reproducibility of discriminant function analyses. [PDF]

open access: yes, 2015
Data are the foundation of empirical research, yet all too often the datasets underlying published papers are unavailable, incorrect, or poorly curated. This is a serious issue, because future researchers are then unable to validate published results or ...
Albert, Arianne YK   +5 more
core   +3 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Análise multivariada das medidas morfométricas de potros da raça Mangalarga Marchador: análise discriminante Multivariate analysis of body measures in Mangalarga Marchador foals: discriminant analysis

open access: yesRevista Brasileira de Zootecnia, 2005
Objetivou-se, com este trabalho, avaliar as medidas morfométricas de potros e potras da raça Mangalarga Marchador utilizando a análise discriminante. As medidas corporais foram feitas na semana do nascimento dos potros, em 55 potros e 41 potras; aos seis
Luís Fernando Batista Pinto   +5 more
doaj   +1 more source

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

open access: yesAdvanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan   +11 more
wiley   +1 more source

Prevalence of Eimeria spp. in calves from dairy farms in northern Paraná state, Brazil

open access: yesRevista Brasileira de Parasitologia Veterinária, 2018
Bovine coccidiosis is a disease of major importance in cattle herds across the world. The disorder mainly affects young calves, and E. bovis and E. zuernii are considered the most pathogenic species of the genus, however, E.
Sérgio Tosi Cardim   +10 more
doaj   +1 more source

Development of virtual morphometric globes using Blender

open access: yes, 2015
Virtual globes - programs implementing interactive three-dimensional (3D) models of planets - are increasingly used in geosciences. Global morphometric models can be useful for tectonic and planetary studies.
Filippov, S. V., Florinsky, I. V.
core   +1 more source

Home - About - Disclaimer - Privacy